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尸体肾移植中抗淋巴细胞球蛋白的对照试验。

Antilymphocyte globulin in cadaveric renal transplantation--a controlled trial.

作者信息

Jakobsen A, Sødal G, Flatmark A, Thorsby E

出版信息

Scand J Urol Nephrol Suppl. 1977(42):94-6.

PMID:356233
Abstract

In a prospective, controlled study, 40 patients receiving a cadaveric renal transplant (first grafts) were randomized into two groups. Twenty patients were given antilymphocyte globulin (Behringwerke AHLG) in a dose of 10 mg/kg body weight for a total no. of 25 times in combination with a standard regimen of prednisone and azathioprine. Graft survival and graft function were similar in the two groups both at 18 and 30 months post transplantation. No serious side effects of the ALG treatment were observed.

摘要

在一项前瞻性对照研究中,40例接受尸体肾移植(首次移植)的患者被随机分为两组。20例患者接受抗淋巴细胞球蛋白(贝林韦尔克抗淋巴细胞球蛋白)治疗,剂量为10mg/kg体重,共给药25次,同时联合泼尼松和硫唑嘌呤的标准治疗方案。移植后18个月和30个月时,两组的移植物存活率和移植物功能相似。未观察到抗淋巴细胞球蛋白治疗的严重副作用。

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