Sansom J R, Barnes A D, Hall C L
Postgrad Med J. 1976;52(5 Suppl):75-8.
In controlled randomized study of antilymphocyte globulin (ALG) in 100 cadaveric renal transplants, 15 patients receiving a second transplant were excluded. Ofthe first transplants, 42 were in the control and 43 in the ALG group. The two groups were similar. The ALG used was either prodduced in our laboratories or obtained from a commerical source. It was observed that ALG produced a significant lymphopenia, that the oliguric phase of the ALG group was half that of the controls, and that the ALG group although less likely to suffer rejection episodes responded significantly better when treated than did those in the control group.
在一项针对100例尸体肾移植患者使用抗淋巴细胞球蛋白（ALG）的对照随机研究中，15例接受二次移植的患者被排除在外。在首次移植中，42例在对照组，43例在ALG组。两组情况相似。所使用的ALG要么是在我们实验室生产的，要么是从商业渠道获得的。观察到ALG导致明显的淋巴细胞减少，ALG组的少尿期是对照组的一半，并且ALG组虽然发生排斥反应的可能性较小，但在接受治疗时的反应明显优于对照组。
