Schiaffino E, Bestetti-Bosisio M, Toia G, Onida L, Riboli P, Schmid C
Pathol Res Pract. 1986 Dec;181(6):755-60. doi: 10.1016/S0344-0338(86)80052-8.
Lymph node biopsies from 16 cases of intravenous drug addicts with lymphadenopathy syndrome (LAS) have been examined at the electron microscope. The main ultrastructural alterations observed in the lymphocytes, dendritic reticulum cells and endothelial cells were tubulo-reticular structures (TRS), test tube and ring shaped forms (TRF) and nuclear pockets (NP). Images suggesting virus budding from lymphocytes and virus-like particles have also been found in 9 out of the 16 cases. The possibility to correlate the latter findings with a better knowledge of LAS evolution and prognosis is discussed.
对16例患有淋巴结病综合征（LAS）的静脉注射吸毒者的淋巴结活检组织进行了电子显微镜检查。在淋巴细胞、树突状网状细胞和内皮细胞中观察到的主要超微结构改变为管状网状结构（TRS）、试管状和环状结构（TRF）以及核袋（NP）。在16例中的9例中还发现了提示病毒从淋巴细胞中出芽和病毒样颗粒的图像。讨论了将后一种发现与更深入了解LAS的演变和预后相关联的可能性。
