College of Biological, Chemical Sciences and Engineering, Jiaxing University, Jiaxing 314001, China.
College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, China.
Biosensors (Basel). 2022 May 11;12(5):326. doi: 10.3390/bios12050326.
A novel electrochemical sensor designed to recognize and detect tartrazine (TZ) was constructed based on a molecularly imprinted polydopamine (MIPDA)-coated nanocomposite of platinum cobalt (PtCo) nanoalloy-functionalized graphene oxide (GO). The nanocomposites were characterized and the TZ electrochemical detection performance of the sensor and various reference electrodes was investigated. Interestingly, the synergistic effect of the strong electrocatalytic activity of the PtCo nanoalloy-decorated GO and the high TZ recognition ability of the imprinted cavities of the MIPDA coating resulted in a large and specific response to TZ. Under the optimized conditions, the sensor displayed linear response ranges of 0.003-0.180 and 0.180-3.950 µM, and its detection limit was 1.1 nM (S/N = 3). The electrochemical sensor displayed high anti-interference ability, good stability, and adequate reproducibility, and was successfully used to detect TZ in spiked food samples. Comparison of important indexes of this sensor with those of previous electrochemical sensors for TZ revealed that this sensor showed improved performance. This surface-imprinted sensor provides an ultrasensitive, highly specific, effective, and low-cost method for TZ determination in foodstuffs.
一种基于聚多巴胺（PDA）涂层的铂钴（PtCo）纳米合金功能化氧化石墨烯（GO）纳米复合材料设计的新型电化学传感器，用于识别和检测柠檬黄（TZ）。对纳米复合材料进行了表征，并研究了传感器和各种参比电极对 TZ 的电化学检测性能。有趣的是，PtCo 纳米合金修饰的 GO 的强电催化活性与 MIPDA 涂层的印迹腔对 TZ 的高识别能力的协同作用，导致对 TZ 产生了大而特异的响应。在优化条件下，传感器对 TZ 的线性响应范围为 0.003-0.180 和 0.180-3.950 µM，检测限为 1.1 nM（S/N = 3）。电化学传感器具有高抗干扰能力、良好的稳定性和足够的重现性，并成功用于检测加标食品样品中的 TZ。与先前用于 TZ 的电化学传感器的重要指标进行比较表明，该传感器的性能得到了提高。这种表面印迹传感器为食品中 TZ 的测定提供了一种超灵敏、高特异性、有效且低成本的方法。
