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急诊子宫动脉栓塞术用于治疗晚期宫颈癌患者的腹腔内大出血和子宫破裂

Emergency Uterine Artery Embolization Used for Managing Profuse Intra-Abdominal Bleeding and Uterine Rupture in a Patient with Advanced Cervical Cancer.

作者信息

Habanova Hana, Mikula Peter, Tvrdik Tomas, Dedinska Eva, Komaromy Katarina, Rusnak Igor

机构信息

1st Clinic of Gynecology and Obstetrics, Slovak Medical University and University Hospital Bratislava, Limbova 5, 83305 Bratislava, Slovakia.

Clinic of Radiology, Faculty of Medicine of Comenius University, Slovak Medical University, Limbova 5, 83305 Bratislava, Slovakia.

出版信息

Diagnostics (Basel). 2022 Apr 26;12(5):1081. doi: 10.3390/diagnostics12051081.

DOI:10.3390/diagnostics12051081
PMID:35626237
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9139450/
Abstract

Advanced cervical cancer can lead to life-threatening vaginal bleeding. Emergency uterine artery embolization (UAE) has been successfully used in such cases to achieve hemostasis. Our case demonstrates the unusual emergency use of this procedure to cease heavy hemorrhage, which led to hematometra, uterine rupture and hemoperitoneum in a patient with a large tumor in the cervical region. Vaginal bleeding was minimal in this case. The emergency UAE controlled the bleeding, and the patient was scheduled for laparotomy soon after the procedure, where a supracervical hysterectomy with bilateral salpingo-oophorectomy and the removal of blood and blood clots was performed. Since the tumor primarily involved the parametria, a sample was taken for histopathology examination with the following result: squamocellular HPV-associated cervical carcinoma. The postoperative management of the patient consisted of combined chemotherapy and radiotherapy, with no complications related to the UAE. Four months after the procedure the patient is reasonably well. Urgent surgery was not the optimal decision because of the alteration of the pelvic anatomy by the tumor, and thus the UAE enabled us to manage this life-threatening condition quickly, allowing us to best prepare the patient for further therapeutic modalities.

摘要

晚期宫颈癌可导致危及生命的阴道出血。紧急子宫动脉栓塞术(UAE)已成功应用于此类病例以实现止血。我们的病例展示了该手术在紧急情况下的特殊应用,用于止住大出血,此大出血导致一名宫颈区域有大肿瘤的患者出现子宫积血、子宫破裂和腹腔积血。该病例中阴道出血很少。紧急UAE控制了出血,术后患者很快被安排进行剖腹手术,术中进行了次全子宫切除术加双侧输卵管卵巢切除术以及清除血液和血凝块。由于肿瘤主要累及子宫旁组织,取了样本进行组织病理学检查,结果如下:人乳头瘤病毒相关的鳞状细胞宫颈癌。患者术后管理包括联合化疗和放疗,未出现与UAE相关的并发症。术后四个月患者情况尚可。由于肿瘤改变了盆腔解剖结构,紧急手术并非最佳选择,因此UAE使我们能够迅速处理这一危及生命的状况,从而能够为患者进一步的治疗方式做好最佳准备。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5200/9139450/8980c7a5be68/diagnostics-12-01081-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5200/9139450/4e44b50b38b5/diagnostics-12-01081-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5200/9139450/e2de8b9c6895/diagnostics-12-01081-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5200/9139450/8980c7a5be68/diagnostics-12-01081-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5200/9139450/4e44b50b38b5/diagnostics-12-01081-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5200/9139450/e2de8b9c6895/diagnostics-12-01081-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5200/9139450/8980c7a5be68/diagnostics-12-01081-g003.jpg

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本文引用的文献

1
Emergency Embolization of Pelvic Vessels in Patients With Locally Advanced Cervical Cancer and Massive Vaginal Bleeding: A Case Series in a Latin American Oncological Center.局部晚期宫颈癌伴大量阴道出血患者盆腔血管的急诊栓塞治疗:拉丁美洲肿瘤中心的病例系列
JCO Glob Oncol. 2020 Sep;6:1376-1383. doi: 10.1200/GO.20.00239.
2
Palliative interventions for controlling vaginal bleeding in advanced cervical cancer.晚期宫颈癌控制阴道出血的姑息性干预措施。
Cochrane Database Syst Rev. 2019 Mar 19;3(3):CD011000. doi: 10.1002/14651858.CD011000.pub3.