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神经内分泌肿瘤心脏转移的前沿成像:来自一组病例的经验教训

Cutting-Edge Imaging of Cardiac Metastases from Neuroendocrine Tumors: Lesson from a Case Series.

作者信息

El Ghannudi Soraya, Ouvrard Eric, Mikail Nidaa, Leroy Freschini Benjamin, Schindler Thomas H, Imperiale Alessio

机构信息

Nuclear Medicine, Institut de Cancérologie de Strasbourg Europe (ICANS), University Hospitals of Strasbourg, 67093 Strasbourg, France.

Department of Radiology, University Hospitals of Strasbourg, 67098 Strasbourg, France.

出版信息

Diagnostics (Basel). 2022 May 9;12(5):1182. doi: 10.3390/diagnostics12051182.

DOI:10.3390/diagnostics12051182
PMID:35626337
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9139778/
Abstract

With the increasing availability of high-performance medical imaging for the management of patients with neuroendocrine tumors (NETs), a progressive growth of asymptomatic and incidentally detected cardiac metastases (CMs) has been observed in the recent years. In clinical practice, CMs of NENs are often incidentally detected by whole-body Ga-labeled somatostatin analogs or F-fluorodihydroxyphenylalanine positron emission tomography/computed tomography, and afterwards accurately characterized by cardiac magnetic resonance (CMR) and/or gated cardiac computed tomography when CMR is contraindicated or not available. The interpreting physician should familiarize with the main imaging features of CM, a finding that may be encountered in NETs patients more than previously thought. Herein, we present a case series of four patients with CMs from small-intestine NETs highlighting strengths and weaknesses of a multimodality imaging approach in clinical practice.

摘要

随着用于神经内分泌肿瘤(NETs)患者管理的高性能医学成像技术日益普及,近年来已观察到无症状和偶然发现的心脏转移瘤(CMs)呈逐渐增长趋势。在临床实践中,神经内分泌肿瘤的心脏转移瘤常通过全身镓标记的生长抑素类似物或氟代二羟基苯丙氨酸正电子发射断层扫描/计算机断层扫描偶然发现,之后在心脏磁共振成像(CMR)禁忌或无法进行时,通过门控心脏计算机断层扫描对其进行准确特征描述。解读医生应熟悉心脏转移瘤的主要影像学特征,这一发现可能在NETs患者中比以前认为的更为常见。在此,我们展示了一组来自小肠NETs的4例心脏转移瘤患者病例系列,突出了多模态成像方法在临床实践中的优缺点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34f6/9139778/948d48efa8b6/diagnostics-12-01182-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34f6/9139778/6a084bb199b2/diagnostics-12-01182-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34f6/9139778/b88cdfe450ee/diagnostics-12-01182-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34f6/9139778/948d48efa8b6/diagnostics-12-01182-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34f6/9139778/6a084bb199b2/diagnostics-12-01182-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34f6/9139778/b88cdfe450ee/diagnostics-12-01182-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34f6/9139778/948d48efa8b6/diagnostics-12-01182-g008.jpg

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Clin Endocrinol (Oxf). 2021 Oct;95(4):595-605. doi: 10.1111/cen.14527. Epub 2021 Jun 19.
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