Qammar Naseha Wafa, Orinaitė Ugnė, Šiaučiūnaitė Vaiva, Vainoras Alfonsas, Šakalytė Gintarė, Ragulskis Minvydas
Department of Mathematical Modelling, Kaunas University of Technology, Studentu St. 50-146, LT-51368 Kaunas, Lithuania.
Institute of Cardiology, Lithuanian University of Health Sciences, Sukileliu St. 17, LT-50161 Kaunas, Lithuania.
Diagnostics (Basel). 2022 May 18;12(5):1256. doi: 10.3390/diagnostics12051256.
In this study, two categories of persons with normal and high ABP are subjected to the bicycle stress test (9 persons with normal ABP and 10 persons with high ABP). All persons are physically active men but not professional sportsmen. The mean and the standard deviation of age is 41.11 ± 10.21 years; height 178.88 ± 0.071 m; weight 80.53 ± 10.01 kg; body mass index 25.10 ± 2.06 kg/m2. Machine learning algorithms are employed to build a set of rules for the classification of the performance during the stress test. The heart rate, the JT interval, and the blood pressure readings are observed during the load and the recovery phases of the exercise. Although it is obvious that the two groups of persons will behave differently throughout the bicycle stress test, with this novel study, we are able to detect subtle variations in the rate at which these changes occur. This paper proves that these differences are measurable and substantial to detect subtle differences in the self-organization of the human cardiovascular system. It is shown that the data collected during the load phase of the stress test plays a more significant role than the data collected during the recovery phase. The data collected from the two groups of persons are approximated by Gaussian distribution. The introduced classification algorithm based on the statistical analysis and the triangle coordinate system helps to determine whether the reaction of the cardiovascular system of a new candidate is more pronounced by an increased heart rate or an increased blood pressure during the stress test. The developed approach produces valuable information about the self-organization of human cardiovascular system during a physical exercise.
在本研究中,两类血压正常和血压高的人接受了自行车应激试验(9名血压正常者和10名血压高者)。所有受试者均为体力活动的男性,但不是职业运动员。年龄的平均值和标准差为41.11±10.21岁;身高178.88±0.071米;体重80.53±10.01千克;体重指数25.10±2.06千克/平方米。采用机器学习算法建立一套规则,用于对应激试验期间的表现进行分类。在运动的负荷和恢复阶段观察心率、JT间期和血压读数。虽然很明显两组人在整个自行车应激试验中的表现会有所不同,但通过这项新颖的研究,我们能够检测到这些变化发生速率的细微差异。本文证明,这些差异是可测量的,并且对于检测人体心血管系统自组织中的细微差异具有重要意义。结果表明,应激试验负荷阶段收集的数据比恢复阶段收集的数据发挥更重要的作用。两组人收集的数据近似服从高斯分布。引入的基于统计分析和三角形坐标系的分类算法有助于确定新受试者在应激试验期间心血管系统的反应是通过心率增加还是血压升高更为明显。所开发的方法产生了关于体育锻炼期间人体心血管系统自组织的有价值信息。