脑的组织结构与人类疾病

Departments of Molecular Genetics and Molecular Neuroscience, Weizmann Institute of Science, Rehovot 7610001, Israel.

The Robert H. Smith Faculty of Agricultural, Food and Environmental Sciences, School of Veterinary Medicine, The Hebrew University of Jerusalem, Rehovot 7612001, Israel.

Cells. 2022 May 14;11(10):1642. doi: 10.3390/cells11101642.

The cortex is a highly organized structure that develops from the caudal regions of the segmented neural tube. Its spatial organization sets the stage for future functional arealization. Here, we suggest using a developmental perspective to describe and understand the etiology of common cortical malformations and their manifestation in the human brain.

大脑皮层是一个高度组织化的结构，由分节的神经管尾部区域发育而来。其空间组织为未来的功能区域化奠定了基础。在这里，我们建议使用发展的观点来描述和理解常见皮质畸形的病因及其在人类大脑中的表现。