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活动状态在接受心脏康复的心力衰竭患者心血管再住院风险中起重要作用:一项回顾性队列研究。

Mobility Status Plays an Important Role in the Risk of Cardiovascular Rehospitalizations in Patients with Heart Failure Undergoing Cardiac Rehabilitation: A Retrospective Cohort Study.

作者信息

Chen Po-Cheng, Yang Tsung-Hsun, Wu Po-Jui, Wang Lin-Yi, Chen Shyh-Ming

机构信息

Department of Physical Medicine and Rehabilitation, Kaohsiung Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Kaohsiung City 833, Taiwan.

Section of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Kaohsiung City 833, Taiwan.

出版信息

J Pers Med. 2022 Apr 22;12(5):675. doi: 10.3390/jpm12050675.

Abstract

The aim of this study was to investigate the association between mobility status and cardiovascular rehospitalizations in patients with heart failure undergoing cardiac rehabilitation. This retrospective cohort study included patients with heart failure undergoing cardiac rehabilitation. Mobility status was evaluated using functional ambulation categories (FAC), and each cardiovascular hospitalization was recorded by the case manager. A Poisson regression model was used to analyze the association between mobility status and cardiovascular rehospitalizations. This study included 154 patients with heart failure undergoing cardiac rehabilitation. For cardiovascular rehospitalizations within 6 months, the Poisson regression model reported that the impaired mobility group had a higher risk than the fair mobility group (incidence rate ratio (IRR) = 2.38, 95% CI 1.27-4.46, = 0.007). For cardiovascular rehospitalizations within 12 months, the Poisson regression model also reported that the impaired mobility group had a higher risk than the fair mobility group (IRR = 1.91, 95% CI 1.16-3.13, = 0.010). Other covariates, such as LVEF, peak oxygen consumption, and PAOD, could have impacted the risk of cardiovascular rehospitalizations. Among patients with heart failure undergoing cardiac rehabilitation, the impaired mobility group had a twofold risk of cardiovascular rehospitalizations, compared with the fair mobility group within both 6 and 12 months.

摘要

本研究的目的是调查接受心脏康复治疗的心力衰竭患者的活动状态与心血管再住院之间的关联。这项回顾性队列研究纳入了接受心脏康复治疗的心力衰竭患者。使用功能性步行分类(FAC)评估活动状态,病例管理员记录每次心血管住院情况。采用泊松回归模型分析活动状态与心血管再住院之间的关联。本研究纳入了154例接受心脏康复治疗的心力衰竭患者。对于6个月内的心血管再住院情况,泊松回归模型显示,活动能力受损组的风险高于活动能力中等组(发病率比(IRR)=2.38,95%置信区间1.27 - 4.46,P = 0.007)。对于12个月内的心血管再住院情况,泊松回归模型也显示,活动能力受损组的风险高于活动能力中等组(IRR = 1.91,95%置信区间1.16 - 3.13,P = 0.010)。其他协变量,如左心室射血分数、峰值耗氧量和外周动脉疾病,可能会影响心血管再住院的风险。在接受心脏康复治疗的心力衰竭患者中,与活动能力中等组相比,活动能力受损组在6个月和12个月内发生心血管再住院的风险增加了两倍。

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