Tamarozzi R, Bedani P L, Pinna L, Ceruti S, Gilli P, Storari A, Bergami M, Farinelli A
Radiol Med. 1987 Mar;73(3):154-8.
Bone damage in hand phalanges has been evaluated with reference to age and duration of hemodialysis (on the basis of 248 radiological observations), in 93 cases with chronic renal failure (age: 20-59 years). These patients were on regular dialytic treatment (RDT) from 1 to 138 months. 72% of the patients underwent several periodic (annual) controls using the mammographic technique. The radiologic evaluations have been arranged into groups according to age. Skeletal damage was more evident when RDT was prolonged. Bone damage increases with age in the first 48 months; afterwards, on the contrary, bone changes were more evident in middle aged patients. At the beginning of RDT, acroosteolysis was the most important change always present. Both subperiosteal and intracortical resorption are more evident increasing age and duration of RDT. Radiological changes give a clear picture of the possible histo-morphologic pattern that characterizes uremic osteodystrophy.
基于248例放射学观察结果，对93例年龄在20至59岁之间的慢性肾衰竭患者手部指骨的骨损伤情况进行了评估，评估参考了年龄和血液透析时长（这些患者接受规律透析治疗的时间为1至138个月）。72%的患者使用乳腺X线摄影技术进行了多次定期（每年一次）检查。放射学评估已根据年龄分组。当规律透析治疗时间延长时，骨骼损伤更为明显。在最初的48个月内，骨损伤随年龄增长而增加；然而，在这之后，相反地，中年患者的骨骼变化更为明显。在规律透析治疗开始时，肢端骨质溶解是始终存在的最重要变化。骨膜下和皮质内吸收均随年龄增长和规律透析治疗时间延长而更为明显。放射学变化清晰地呈现了可能表征尿毒症性骨营养不良的组织形态学模式。
