脑海绵状血管畸形的个性化治疗方案

Hoffman Jessa E, Wittenberg Blake, Morel Brent, Folzenlogen Zach, Case David, Roark Christopher, Youssef Samy, Seinfeld Joshua

Department of Neurosurgery, University of Colorado, Aurora, CO 80045, USA.

J Pers Med. 2022 May 20;12(5):831. doi: 10.3390/jpm12050831.

The diagnosis and treatment of cerebral cavernous malformations (CCMs), or cavernomas, continues to evolve as more data and treatment modalities become available. Intervention is necessary when a lesion causes symptomatic neurologic deficits, seizures, or has high risk of continued hemorrhage. Future medical treatment directions may specifically target the pathogenesis of these lesions. This review highlights the importance of individualized treatment plans based on specific CCM characteristics.

随着更多数据和治疗方式的出现，脑海绵状血管畸形（CCM）或海绵状瘤的诊断和治疗不断发展。当病变导致有症状的神经功能缺损、癫痫发作或有持续出血的高风险时，就需要进行干预。未来的药物治疗方向可能会专门针对这些病变的发病机制。这篇综述强调了基于特定CCM特征制定个体化治疗方案的重要性。