Zhao Biao, Deng Jinrui, Deng Jianping
State Key Laboratory of Chemical Resource Engineering and ‡College of Materials Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, China.
State Key Laboratory of Chemical Resource Engineering and College of Materials Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, China.
ACS Macro Lett. 2017 Jan 17;6(1):6-10. doi: 10.1021/acsmacrolett.6b00808. Epub 2016 Dec 14.
Chiral micelles have been drawing ever-increasing attention because of their potentials in mimicking the unique stereochemical effects of enzymes. This article reports on the first success in preparing chiral micelles through self-assembly of helical polyacetylene bearing cholic acid pendants. The micelles were further used as chiral nanoreactor, in which achiral acetylenic monomer smoothly underwent helix-sense-selective polymerization (HSSP). The HSSPs directly established optically active core/shell nanoparticles whose shell and core both were constructed by helical polymers. The shells (or micelles) provided a protective effect for the preferably induced one-handed helical polymer chains in the cores. The present work provides insights into the self-assembly of chiral helical polymers, and also provides a powerful strategy for constructing novel chiral polymer nanoarchitectures.
手性胶束因其在模拟酶独特立体化学效应方面的潜力而受到越来越多的关注。本文报道了通过带有胆酸侧基的螺旋状聚乙炔自组装制备手性胶束的首次成功。这些胶束进一步用作手性纳米反应器，其中非手性炔单体顺利进行了螺旋方向选择性聚合（HSSP）。HSSP直接构建了光学活性的核/壳纳米粒子，其壳和核均由螺旋聚合物构成。壳（或胶束）为核中优先诱导的单手螺旋聚合物链提供了保护作用。目前的工作为手性螺旋聚合物的自组装提供了见解，也为构建新型手性聚合物纳米结构提供了有力策略。
