School of Nursing, Sun Yat-sen University, Guangzhou, Guangdong, China.
Department of Gastric Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Nutr Cancer. 2022;74(9):3312-3321. doi: 10.1080/01635581.2022.2074474. Epub 2022 May 27.
To explore compliance with oral nutritional supplementation (ONS) and to identify the risk factors for noncompliance among gastric cancer patients based on the health belief model (HBM).
This prospective, observational study included gastric cancer patients at nutritional risk who were prescribed ONS from July to September 2020. Demographic factors, clinical factors, ONS-related factors, social factors and variables derived from the HBM were collected. The outcome of interest was compliance with ONS, which was measured by self-reported intake of ONS. Uni- and multivariate analyses of potential risk factors for noncompliance were performed.
A total of 162 gastric cancer patients in the preoperative and adjuvant chemotherapy periods were analyzed. The compliance rate with ONS was 24.7%. Univariate analysis identified thirteen variables as risk factors for decreased compliance. Multivariate logistic analysis indicated that ONS compliance was independently associated with the treatment period, perceived barriers to ONS, the motivation to take ONS, and the timing of taking ONS.
This study showed that overall ONS compliance among gastric cancer patients was notably low. Patients in the chemotherapy treatment period who took ONS at random times each day perceived more barriers to taking ONS and had a lower level of motivation were associated with lower compliance with ONS.
基于健康信念模型(HBM),探讨胃癌患者口服营养补充(ONS)的依从性,并确定其不依从的危险因素。
本前瞻性观察研究纳入了 2020 年 7 月至 9 月间被开具 ONS 处方且存在营养风险的胃癌患者。收集了人口统计学因素、临床因素、ONS 相关因素、社会因素以及源自 HBM 的变量。感兴趣的结局是 ONS 的依从性,通过自我报告的 ONS 摄入量来衡量。对不依从的潜在危险因素进行了单因素和多因素分析。
分析了 162 例术前和辅助化疗期的胃癌患者。ONS 的依从率为 24.7%。单因素分析确定了 13 个变量是降低依从性的危险因素。多因素 logistic 分析表明,ONS 依从性与治疗期、ONS 感知障碍、ONS 服用动机以及ONS 服用时间独立相关。
本研究表明,胃癌患者总体 ONS 依从性明显较低。化疗期间每日随机时间服用 ONS 的患者感知到更多的 ONS 服用障碍,并且服用动机较低,与 ONS 依从性较低相关。