Maharajgunj Medical Campus, Institute of Medicine, Tribhuvan University, Maharajgunj, Kathmandu, Nepal.
Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal.
JNMA J Nepal Med Assoc. 2022 May 5;60(249):419-424. doi: 10.31729/jnma.7457.
Valvular heart disease continues to cause significant morbidity and mortality around the world, with rheumatic heart disease accounting for the bulk of cases in developing nations. The aim of this study is to find out the prevalence of rheumatic heart disease among patients with valvular heart disease admitted to the in-patient department of a tertiary care centre.
A descriptive cross-sectional study was conducted from December, 2018 to December, 2020 at a tertiary care centre after receiving ethical approval from the Institutional Review [Reference number: 395 (6-11) e2 077/078]. Patients of age ≥18 years presenting with valvular manifestations of any disease diagnosed by transthoracic echocardiography were included and patients other than Nepalese nationals were excluded. Convenience sampling was done and a sample size of 327 was taken. Data were collected, entered and analyzed using the Statistical Package for the Social Sciences version 22.0. Point estimate at a 95% Confidence Interval was calculated along with frequency and percentages for binary data.
Among 327 patients, the prevalence of rheumatic heart disease was found to be 237 (72.47%) (67.63-77.31 at 95% Confidence Interval).
The prevalence of rheumatic heart disease was similar to the other similar studies conducted in similar settings.
epidemiology; prevalence; rheumatic heart disease.
引言:瓣膜性心脏病在全球范围内仍导致大量发病率和死亡率,风湿性心脏病在发展中国家占大多数病例。本研究旨在了解在三级保健中心住院部就诊的瓣膜性心脏病患者中风湿性心脏病的患病率。
方法:在获得机构审查委员会的伦理批准后[参考编号:395(6-11)e2 077/078],于 2018 年 12 月至 2020 年 12 月在三级保健中心进行了一项描述性横断面研究。纳入年龄≥18 岁且经胸超声心动图诊断为任何疾病出现瓣膜表现的患者,排除非尼泊尔国民的患者。采用便利抽样法,抽取样本量为 327 例。使用社会科学统计软件包 22.0 版收集、输入和分析数据。计算了 95%置信区间的点估计值以及二进制数据的频率和百分比。
结果:在 327 例患者中,风湿性心脏病的患病率为 237 例(72.47%)(95%置信区间为 67.63-77.31)。
结论:风湿性心脏病的患病率与在类似环境中进行的其他类似研究相似。
关键词:流行病学;患病率;风湿性心脏病。