Nepal Medical College and Teaching Hospital, Jorpati, Kathmandu, Nepal.
Department of Statistics, Nepal Commerce Campus, Tribhuwan University, Minbhawan, Kathmandu, Nepal.
JNMA J Nepal Med Assoc. 2022 Apr 15;60(248):340-343. doi: 10.31729/jnma.7434.
Alcoholic liver diseases comprise a spectrum of liver diseases including fatty liver, alcoholic hepatitis, and cirrhosis. Diagnosis at advanced stages is frequent for this condition and data regarding the prevalence of such patients at early stages are limited. The aim of this study is to find out the prevalence of alcoholic liver disease among patients admitted to the Department of Internal Medicine of a tertiary care centre.
A descriptive cross-sectional study was conducted among 538 patients admitted to the Department of Internal Medicine of a tertiary care centre in Nepal between 3rd November, 2021 and 22nd February, 2022 after receiving ethical approval from the Institutional Review Committee of the hospital (Reference number: 006-078/079). Convenience sampling was done. Data were collected and entered in Microsoft Excel and analysed using Statistical Package for the Social Sciences version 24.0. Point estimate at 95% Confidence Interval was calculated along with frequency and percentage for binary data along with mean and standard deviation for continuous data.
Among 538 patients, alcoholic liver disease was seen in 42 (7.80%) (5.53-10.07 at 95% Confidence Interval). The mean age of the patients was 53.85±10.88 years. Among these patients 25 (59.52%) were males and 17 (40.47%) of them were females.
Our study showed that the prevalence of alcoholic liver disease was lower as compared to similarly reported literature.
alcoholic liver diseases; jaundice; liver function test; Nepal.
酒精性肝病包括一系列肝脏疾病，包括脂肪肝、酒精性肝炎和肝硬化。这种疾病在晚期诊断较为常见，而早期患者的患病率数据有限。本研究旨在了解尼泊尔一家三级保健中心内科住院患者中酒精性肝病的患病率。
在获得医院机构审查委员会的伦理批准后（参考编号：006-078/079），我们于 2021 年 11 月 3 日至 2022 年 2 月 22 日期间对尼泊尔一家三级保健中心内科的 538 名住院患者进行了一项描述性横断面研究。采用便利抽样法。数据收集并输入 Microsoft Excel 中，并使用统计软件包 24.0 进行分析。计算了 95%置信区间的点估计值，以及二进制数据的频率和百分比，以及连续数据的均值和标准差。
在 538 名患者中，有 42 名（7.80%）（95%置信区间为 5.53-10.07）患有酒精性肝病。患者的平均年龄为 53.85±10.88 岁。在这些患者中，25 名（59.52%）为男性，17 名（40.47%）为女性。
与类似报道的文献相比，我们的研究表明，酒精性肝病的患病率较低。
酒精性肝病；黄疸；肝功能检查；尼泊尔。
