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异基因干细胞移植后患者的肾脏损伤。

KIDNEY DAMAGE IN PATIENTS AFTER ALLOGENEIC STEM CELL TRANSPLANTATION.

机构信息

WARSAW MEDICAL UNIVERSITY, WARSAW, POLAND.

出版信息

Wiad Lek. 2022;75(4 pt 1):877-880. doi: 10.36740/WLek202204123.

DOI:10.36740/WLek202204123
PMID:35633364
Abstract

The aim of the review is to present the most common renal complications after HSCT such as acute kidney injury, chronic kidney disease glomerulopathies. HSCT is a critical therapy for many cancer patients with cancer, as well as patients with some other nonmalignant hematologic disorders and certain congenital immune deficiencies. Kidney complications after HSCT in a form of acute kidney injury is associated with significant morbidity and worse patient outcome. In addition, risk of chronic kidney disease is also increased following HSCT. It is very important to be aware, prevent, early recognize and treat renal damage to improve kidney and patient survival.

摘要

本综述旨在介绍 HSCT 后最常见的肾脏并发症,如急性肾损伤、慢性肾脏病肾小球病变。HSCT 是许多癌症患者、某些非恶性血液病患者和某些先天性免疫缺陷患者的重要治疗方法。HSCT 后以急性肾损伤形式出现的肾脏并发症与较高的发病率和较差的患者预后相关。此外,HSCT 后慢性肾脏病的风险也增加。了解、预防、早期识别和治疗肾损伤以改善肾脏和患者生存非常重要。

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