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使用Xpert/RIF Ultra对肺外结核病进行快速分子诊断。

Rapid Molecular Diagnosis of Extra-Pulmonary Tuberculosis by Xpert/RIF Ultra.

作者信息

Rindi Laura

机构信息

Dipartimento di Ricerca Traslazionale e delle Nuove Tecnologie in Medicina e Chirurgia, Università di Pisa, Pisa, Italy.

出版信息

Front Microbiol. 2022 May 11;13:817661. doi: 10.3389/fmicb.2022.817661. eCollection 2022.

DOI:10.3389/fmicb.2022.817661
PMID:35633667
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9130774/
Abstract

Rapid detection of complex and determination of drug resistance are essential for early diagnosis and treatment of tuberculosis (TB). Xpert MTB/RIF Ultra (Xpert Ultra), a molecular test that can simultaneously identify complex and resistance to rifampicin directly on clinical samples, is currently used. Xpert Ultra represents a helpful tool for rapid pulmonary TB diagnosis, especially in patients with paucibacillary infection. The aim of this review is to provide an overview of the diagnostic performance of Xpert Ultra in detection of extra-pulmonary tuberculosis.

摘要

快速检测结核分枝杆菌复合群及耐药性对于结核病（TB）的早期诊断和治疗至关重要。Xpert MTB/RIF Ultra（Xpert Ultra）是一种分子检测方法，可直接在临床样本上同时鉴定结核分枝杆菌复合群和对利福平的耐药性，目前正在使用。Xpert Ultra是快速诊断肺结核的有用工具，尤其是在菌量少的感染患者中。本综述的目的是概述Xpert Ultra在检测肺外结核病方面的诊断性能。

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