Serratrice G, Pouget J
Rev Rhum Mal Osteoartic. 1987 Feb;54(2):105-8.
The Muckle and Well's syndrome corresponding to a transmission of the autosomic dominant type, combines bouts of urticaria, episodes of arthralgias to a shrinking of the ear and a sensory deafness. Sometimes, it evolves into a renal amylosis. Sometimes, as the case presented here, it combines multiple malformations. Its place in nosology is imprecise. It is, at the same time, close to systemic urticaria, sensory deafness, amylosis and specially amylosis of the periodic disease. But the common link between the various elements of the syndrome remains undetermined, for the time being.
麦克尔和韦尔斯综合征属于常染色体显性遗传类型，其症状包括间歇性荨麻疹、关节痛发作、耳部萎缩和感觉性耳聋。有时，它会发展为肾淀粉样变性。有时，如本文所述病例，它还合并多种畸形。其在疾病分类学中的位置并不明确。它同时与全身性荨麻疹、感觉性耳聋、淀粉样变性尤其是周期性疾病的淀粉样变性相近。但目前该综合征各要素之间的共同联系仍未确定。
