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对脑死亡供体进行充分的血流动力学管理能否改善供体器官的获取？

Can adequate hemodynamic management of brain-dead donors improve donor organ procurement?

作者信息

Thet Myat Soe, Verzelloni Sef Alessandra, Sef Davorin

机构信息

Department of Cardiac Surgery, St Bartholomew's Hospital, London EC1A 7BE, United Kingdom.

Department of Anaesthesia and Critical Care, Harefield Hospital, Royal Brompton and Harefield Hospitals, Part of Guy's and St Thomas' NHS Foundation Trust, London UB9 6JH, United Kingdom.

出版信息

World J Transplant. 2022 Apr 18;12(4):79-82. doi: 10.5500/wjt.v12.i4.79.

DOI:10.5500/wjt.v12.i4.79
PMID:35633852
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9048440/
Abstract

There is increasing evidence that adequate donor management with a goal of optimization of organ function is essential to maximize the number of organs that can be procured. Therefore, identification of the cause of hemodynamic instability is crucial in order to direct the right therapy. Several donor management goals for better hemodynamic management including serial echocardiography can guide hemodynamic management in potential donors to increase both number and quality of donor hearts.

摘要

越来越多的证据表明，以优化器官功能为目标进行充分的供体管理对于最大限度地获取可用于移植的器官数量至关重要。因此，识别血流动力学不稳定的原因对于指导正确的治疗至关重要。包括连续超声心动图在内的几个旨在改善血流动力学管理的供体管理目标，可以指导潜在供体的血流动力学管理，以增加供体心脏的数量和质量。

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Life (Basel). 2023 Jun 26;13(7):1443. doi: 10.3390/life13071443.
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The Incidence of Brain-Dead Donors Based on Screening and Management Led by Intensivists.基于由重症监护医生主导的筛查和管理的脑死亡供者的发生率。
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本文引用的文献

1
Hemodynamic management in brain dead donors.脑死亡供体的血流动力学管理
World J Transplant. 2021 Oct 18;11(10):410-420. doi: 10.5500/wjt.v11.i10.410.
2
Utilization of Paragonix SherpaPak for human donor heart preservation.利用 Paragonix SherpaPak 进行人心保存。
Multimed Man Cardiothorac Surg. 2021 Jun 16;2021. doi: 10.1510/mmcts.2021.035.
3
Heart Transplantation in Adult Congenital Heart Disease with the Organ Care System Use: A 4-Year Single-Center Experience.成人心血管病患者使用器官维护系统行心脏移植：4 年单中心经验。
ASAIO J. 2021 Aug 1;67(8):862-868. doi: 10.1097/MAT.0000000000001482.
4
Transesophageal echocardiography instead or in addition to transthoracic echocardiography in evaluating haemodynamic problems in intubated critically ill patients.在评估插管危重症患者的血流动力学问题时，采用经食管超声心动图替代或补充经胸超声心动图。
Ann Transl Med. 2020 Jun;8(12):785. doi: 10.21037/atm.2020.04.09.
5
Improving the Supply and Quality of Deceased-Donor Organs for Transplantation.提高用于移植的已故捐赠者器官的供应和质量。
N Engl J Med. 2018 May 17;378(20):1920-1929. doi: 10.1056/NEJMra1507080.
6
The utility of serial echocardiograms for organ procurement in brain death.系列超声心动图在脑死亡器官获取中的应用价值。
Clin Transplant. 2017 Nov;31(11). doi: 10.1111/ctr.13094. Epub 2017 Oct 15.
7
Active Donor Management During the Hospital Phase of Care Is Associated with More Organs Transplanted per Donor.在医院护理阶段进行积极的供体管理与每个供体移植更多器官相关。
J Am Coll Surg. 2017 Oct;225(4):525-531. doi: 10.1016/j.jamcollsurg.2017.06.014. Epub 2017 Jul 21.
8
Management of the Potential Organ Donor in the ICU: Society of Critical Care Medicine/American College of Chest Physicians/Association of Organ Procurement Organizations Consensus Statement.重症监护病房潜在器官捐献者的管理：危重病医学学会/美国胸科医师学会/器官获取组织协会共识声明
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The joint impact of donor and recipient parameters on the outcome of heart transplantation in Germany after graft allocation.在德国，移植分配后供体和受体参数对心脏移植结果的联合影响。
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Wait, treat and see: echocardiographic monitoring of brain-dead potential donors with stunned heart.等待、治疗并观察：对心脏顿抑的脑死亡潜在供体进行超声心动图监测。
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