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双侧视力丧失孤立出现提示鼻窦低度软骨肉瘤:一种罕见肿瘤的前所未有的表现。

Sino-nasal low-grade chondrosarcoma revealed by isolated bilateral loss of sight: an unprecedented presentation of a rare tumour.

作者信息

Berhili Soufiane, Guerrouaz Mohammed Amine, Oulhouq Yassine, Terrab Fatima Zahra, Moukhlissi Mohammed, Idrissi Fahd El Ayoubi El, Mezouar Loubna

机构信息

Department of Radiation Oncology, Hassan II Oncology Centre, Mohammed VI University Hospital, PK 8 Jerada Road, 60000, Oujda, Morocco.

Faculty of Medicine and Pharmacy, Mohammed Premier University, Oujda, Morocco.

出版信息

Radiol Case Rep. 2022 May 20;17(7):2563-2567. doi: 10.1016/j.radcr.2022.04.026. eCollection 2022 Jul.

DOI:10.1016/j.radcr.2022.04.026
PMID:35634018
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9130089/
Abstract

Chondrosarcomas are malignant cartilage-forming tumors representing less than 0.1% of all head and neck malignancies, and nasal cavity is an exceptional location among them. Clinical presentation could be consisting of either rhinological signs or asymptomatic endonasal mass. None of the previous reports mentioned ophthalmological symptoms at the forefront of the initial presentation. We report a case of sino-nasal low-grade chondrosarcoma in a patient who presented initially with isolated bilateral subtotal blindness, managed by endoscopic resection and adjuvant radiotherapy.

摘要

软骨肉瘤是形成软骨的恶性肿瘤,在所有头颈部恶性肿瘤中占比不到0.1%,鼻腔是其中一个特殊部位。临床表现可能包括鼻科症状或无症状的鼻内肿物。既往报告均未提及首发症状以眼科症状为主。我们报告一例鼻窦低度软骨肉瘤患者,该患者最初表现为单纯双侧近乎失明,经内镜切除及辅助放疗治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df90/9130089/76dd1623a577/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df90/9130089/e483528f8126/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df90/9130089/9ef710e68e47/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df90/9130089/76dd1623a577/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df90/9130089/e483528f8126/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df90/9130089/9ef710e68e47/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df90/9130089/76dd1623a577/gr3.jpg

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1
Sino-nasal low-grade chondrosarcoma revealed by isolated bilateral loss of sight: an unprecedented presentation of a rare tumour.双侧视力丧失孤立出现提示鼻窦低度软骨肉瘤:一种罕见肿瘤的前所未有的表现。
Radiol Case Rep. 2022 May 20;17(7):2563-2567. doi: 10.1016/j.radcr.2022.04.026. eCollection 2022 Jul.
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本文引用的文献

1
Chondrosarcoma of Nasal Cavity: a Rare Entity.鼻腔软骨肉瘤:一种罕见的疾病。
Indian J Surg Oncol. 2020 Sep;11(Suppl 2):288-292. doi: 10.1007/s13193-020-01202-7. Epub 2020 Aug 28.
2
Incidence, outcomes and prognostic factors during 25 years of treatment of chondrosarcomas.软骨肉瘤25年治疗期间的发病率、治疗结果及预后因素
Surg Oncol. 2018 Sep;27(3):402-408. doi: 10.1016/j.suronc.2018.05.009. Epub 2018 May 6.
3
Management of Nasal Septum Chondrosarcoma Occurring in Elderly: A Case Report.老年鼻中隔软骨肉瘤的治疗:一例报告
Cureus. 2017 Jul 20;9(7):e1497. doi: 10.7759/cureus.1497.
4
Correlation between survival and tumour characteristics in patients with chondrosarcoma.软骨肉瘤患者生存与肿瘤特征之间的相关性
J Orthop Surg (Hong Kong). 2015 Dec;23(3):365-9. doi: 10.1177/230949901502300323.
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Low grade chondrosarcoma of the nasal septum.鼻中隔低度恶性软骨肉瘤
World J Clin Cases. 2013 Apr 16;1(1):64-6. doi: 10.12998/wjcc.v1.i1.64.
6
Chondrosarcoma of nose and paranasal sinus - a rare presentation.鼻及鼻窦软骨肉瘤——一种罕见的表现。
Indian J Otolaryngol Head Neck Surg. 2008 Sep;60(3):284-6. doi: 10.1007/s12070-008-0095-9. Epub 2008 Oct 22.
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The clinical management of chondrosarcoma.软骨肉瘤的临床管理
Curr Treat Options Oncol. 2009 Apr;10(1-2):94-106. doi: 10.1007/s11864-009-0088-2. Epub 2009 Feb 24.
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Chondrosarcoma of the sphenoid sinus resected by an endoscopic approach.经鼻内镜手术切除的蝶窦软骨肉瘤
Am J Otolaryngol. 2004 Jul-Aug;25(4):274-7. doi: 10.1016/j.amjoto.2003.12.007.
9
Chondrosarcoma of the nasal septum.鼻中隔软骨肉瘤
Otolaryngol Head Neck Surg. 2001 Jul;125(1):98-100. doi: 10.1067/mhn.2001.116236.
10
National cancer database report on chondrosarcoma of the head and neck.国家癌症数据库关于头颈部软骨肉瘤的报告。
Head Neck. 2000 Jul;22(4):408-25. doi: 10.1002/1097-0347(200007)22:4<408::aid-hed15>3.0.co;2-h.