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鼻腔和鼻窦软骨肉瘤:一种罕见的疾病

Chondrosarcoma of the Nasal Cavity and Paranasal Sinuses: A Rare Entity.

作者信息

Malika El Omri, Ben Njima Marwa, Mouna Bellakhdher, Zeineb Nfikha, Wassim Kemani, Badreddine Sriha, Mohamed Abdelkefi

机构信息

Department of Ear, Nose, Throat and Head and Neck Surgery, Farhat Hached University Hospital, Sousse, Tunisia.

Pathology Department, Farhat Hached University Hospital, Sousse, Tunisia.

出版信息

Ear Nose Throat J. 2024 Apr 24:1455613241249028. doi: 10.1177/01455613241249028.

Abstract

Chondrosarcomas are slow-growing malignant tumors that originate in cartilaginous structures. They typically manifest in the head and neck region, with a preference for the maxillofacial skeleton, particularly the mandible and maxilla. However, chondrosarcoma of the sinonasal tract is exceptionally rare, and only few cases have been reported. This report details the case of a 43-year-old woman who incidentally discovered chondrosarcoma in the maxillary and ethmoid sinuses with nasal extension. Subsequently, the patient underwent surgery via a paralatero-nasal approach with adjuvant radiotherapy. The aim of this study was to describe the clinical findings, management, and outcome of sinonasal tract chondrosarcoma. The primary treatment for chondrosarcomas remains surgery, with a transnasal endoscopic approach offering a viable option for complete resection in select cases.

摘要

软骨肉瘤是起源于软骨结构的生长缓慢的恶性肿瘤。它们通常表现在头颈部区域,尤其好发于颌面骨骼,特别是下颌骨和上颌骨。然而,鼻窦软骨肉瘤极为罕见,仅有少数病例报道。本报告详细介绍了一名43岁女性偶然发现上颌窦和筛窦软骨肉瘤并累及鼻腔的病例。随后,该患者通过鼻旁入路手术并接受辅助放疗。本研究的目的是描述鼻窦软骨肉瘤的临床表现、治疗方法及预后。软骨肉瘤的主要治疗方法仍然是手术,经鼻内镜手术在某些病例中为完整切除提供了可行的选择。

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