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青少年代谢性减重手术后心理、身体和社会因素的短期变化:一项全国性前瞻性队列研究

Short-Term Changes in Mental, Physical, and Social Factors After Metabolic Bariatric Surgery in Adolescents: A Nationwide Prospective Cohort Study.

作者信息

Goldenshluger Ariela, Maor Tamar, Via-Kagan Renana, Zelekha Orly, Gepner Yftach

机构信息

Department of Epidemiology and Preventive Medicine, Sackler Faculty of Medicine, School of Public Health, Sylvan Adams Sports Institute, Tel-Aviv University, Tel-Aviv, Israel.

Israel Center for Disease Control, Ministry of Health, Jerusalem, Israel.

出版信息

Front Nutr. 2022 May 12;9:878202. doi: 10.3389/fnut.2022.878202. eCollection 2022.

Abstract

BACKGROUND

Metabolic bariatric surgery (MBS) is an effective treatment for adolescents with severe obesity. However, changes in mental, physical, and social factors, as well as their association with the extent of excess weight loss (%EWL) after MBS, remain controversial.

METHODS

We followed 97 adolescents (64% females, aged 17 ± 0.9 years, BMI 46.1 ± 5.9 kg/m) before and 9 months following MBS in a multi-center, prospective cohort study. Changes in mental, physical, and social factors were assessed by self-reported questionnaires, and associations with %EWL were evaluated after adjustment for potential confounders.

RESULTS

The body mass index (BMI) decreased by 30%, and all physical parameters significantly improved ( ≤ 0.001). Energy level increased by 24%, mood level by 14%, and mental health by 9.5% ( ≤ 0.002). Social parameters were also improved, with a significant decrease in social rejection ( = 0.02), and an increase in participation in after-school social activities ( = 0.008). Mental health improvement was associated with baseline social rejection (r = 0.514, < 0.001). The improvement in all factors was not related to the extent of %EWL.

CONCLUSION

Metabolic bariatric surgery MBS in adolescents led to a meaningful decrease in BMI and to an improvement in short-term physical, mental, and social factors that were not related to %EWL. Patients experiencing social rejection may improve their mental health following BS.

摘要

背景

代谢性减肥手术(MBS)是治疗重度肥胖青少年的有效方法。然而,心理、身体和社会因素的变化及其与MBS后超重减轻程度(%EWL)的关联仍存在争议。

方法

在一项多中心前瞻性队列研究中,我们对97名青少年(64%为女性,年龄17±0.9岁,BMI 46.1±5.9 kg/m²)在MBS术前及术后9个月进行了随访。通过自我报告问卷评估心理、身体和社会因素的变化,并在对潜在混杂因素进行调整后评估与%EWL的关联。

结果

体重指数(BMI)下降了30%,所有身体参数均显著改善(P≤0.001)。能量水平提高了24%,情绪水平提高了14%,心理健康提高了9.5%(P≤0.002)。社会参数也有所改善,社会排斥显著减少(P = 0.02),课后社交活动参与度增加(P = 0.008)。心理健康的改善与基线社会排斥相关(r = 0.514,P < 0.001)。所有因素的改善均与%EWL的程度无关。

结论

青少年代谢性减肥手术MBS导致BMI有意义地降低,并使短期身体、心理和社会因素得到改善,且这些改善与%EWL无关。经历社会排斥的患者在接受减肥手术后可能会改善其心理健康。

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