Atrah H I, Crawford R J, Gabra G S, Mitchell R
Scott Med J. 1986 Oct;31(4):231-3. doi: 10.1177/003693308603100404.
Twenty-two patients with idiopathic thrombocytopenic purpura were treated with high-dose intravenous immunoglobulin infusions using an intact intravenous immunoglobulin preparation and a product designed for intramuscular administration. Seventeen patients (77%) responded favourably (rise in platelet count to 100 X 10(9)/1 or above). Children responded better than the adults, and the acute cases better than the chronic. Splenectomy and the presence of detectable platelet antibody had no effect on the response rate. Both products induced identical responses.
22例特发性血小板减少性紫癜患者接受了大剂量静脉注射免疫球蛋白治疗,使用的是完整的静脉注射免疫球蛋白制剂和一种专为肌肉注射设计的产品。17例患者(77%)反应良好(血小板计数升至100×10⁹/L或更高)。儿童的反应比成人好,急性病例比慢性病例好。脾切除术和可检测到的血小板抗体的存在对反应率没有影响。两种产品引起的反应相同。