Masson P L, Lurhuma A, Delire M, Lambert M
Presse Med. 1983 Nov 17;12(41):2608-11.
Twelve patients presenting with idiopathic thrombocytopenic purpura were treated with injections of immunoglobulins. A lasting improvement was observed in 1 and a transient improvement in 8. Intramuscular injections appeared to be more effective than intravenous injections. The increase in the number of platelets was accompanied by a decrease of circulating immune complexes. The antigen-antibody reaction observed between the doses of immunoglobulins injected and the patients' sera suggests that immunoglobulins might act by enhancing the elimination of some antigens of infectious origin.
12例特发性血小板减少性紫癜患者接受了免疫球蛋白注射治疗。1例出现持续改善，8例出现短暂改善。肌肉注射似乎比静脉注射更有效。血小板数量增加的同时循环免疫复合物减少。注射的免疫球蛋白剂量与患者血清之间观察到的抗原 - 抗体反应表明，免疫球蛋白可能通过增强对某些感染源抗原的清除而起作用。
