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诺米芬辛引起的血管内溶血和急性肾衰竭。

Intravascular haemolysis and acute renal failure induced by nomifensine.

作者信息

Fulton J D, Briggs J D, Dominiczak A F, Junor B J, Lucie N P

出版信息

Scott Med J. 1986 Oct;31(4):242-3. doi: 10.1177/003693308603100407.

Abstract

Nomifensine is a widely used antidepressant agent with few side-effects but haemolytic anaemia with acute renal failure has been reported with both intermittent therapeutic dosage and self-inflicted overdose. We report here a case of acquired immune haemolytic anaemia with acute renal failure induced by second exposure to a single capsule of nomifensine.

摘要

诺米芬辛是一种广泛使用的抗抑郁药,副作用较少,但有报道称,间歇性治疗剂量和自我过量服用诺米芬辛均会导致溶血性贫血伴急性肾衰竭。我们在此报告一例因再次接触一粒诺米芬辛胶囊而诱发的获得性免疫性溶血性贫血伴急性肾衰竭的病例。

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Fatal immune haemolysis associated with nomifensine.与诺米芬辛相关的致命性免疫性溶血。
Br Med J (Clin Res Ed). 1985 Aug 31;291(6495):606. doi: 10.1136/bmj.291.6495.606.
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[Hemolytic anemia and renal failure caused by nomifensine].
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Fatal immune haemolysis associated with nomifensine.与诺米芬辛相关的致命性免疫性溶血。
Br Med J (Clin Res Ed). 1985 Aug 3;291(6491):311-2. doi: 10.1136/bmj.291.6491.311-a.

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