Buchanan J T, Grillner S
Science. 1987 Apr 17;236(4799):312-4. doi: 10.1126/science.3563512.
A new class of excitatory premotor interneurons that are important in the generation of locomotion in the lamprey has now been described. In the isolated spinal cord, these neurons act simultaneously with their postsynaptic motoneurons during fictive swimming. They are small and numerous, and they monosynaptically excite both motoneurons and inhibitory premotor interneurons. The excitatory postsynaptic potentials are depressed by an antagonist of excitatory amino acids. These interneurons receive reticulospinal input from the brain stem and polysynaptic input form skin afferents. A model of the network underlying locomotion based on the synaptic interactions of these neurons can now be proposed for the lamprey.
现在已经描述了一类新的兴奋性运动前中间神经元，它们在七鳃鳗的运动产生中起着重要作用。在离体脊髓中，这些神经元在模拟游泳时与其突触后运动神经元同时活动。它们体积小且数量众多，通过单突触兴奋运动神经元和抑制性运动前中间神经元。兴奋性突触后电位可被兴奋性氨基酸拮抗剂抑制。这些中间神经元接受来自脑干的网状脊髓输入以及来自皮肤传入神经的多突触输入。基于这些神经元的突触相互作用，现在可以为七鳃鳗提出一个运动基础网络模型。
