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血管造影再血管化后肥胖栓塞猪模型。

Angiographic Revascularization after Bariatric Embolization in a Swine Model.

机构信息

Division of Interventional Radiology, Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland.

Department of Radiology, Piedmont Healthcare, Atlanta, Georgia.

出版信息

J Vasc Interv Radiol. 2022 Jun;33(6):648-652.e2. doi: 10.1016/j.jvir.2022.02.018.

Abstract

This study evaluated fundal arteriole angiographic revascularization after embolization with embolic microspheres of 3 different diameters in a swine model (16 swine, 31 arterioles). In the 50-μm group, 7 of 11 (64%) arterioles recanalized completely, 3 of 11 (27%) arterioles recanalized partially, and 1 of 11 (9%) arterioles had collateralization (no recanalization). In the 100- to 300-μm group, 7 of 10 (70%) arterioles recanalized completely and 3 of 10 (30%) arterioles) recanalized partially. In the 300- to 500-μm group, 7 of 10 (70%) arterioles recanalized completely, 1 of 10 (10%) arterioles recanalized partially, and 2 of 10 (20%) arterioles had collateralization. No difference was found between the groups in the degree of recanalization (P = .64). All embolized arterioles exhibited some degree of angiographic revascularization, irrespective of the microsphere size.

摘要

本研究在猪模型中评估了用 3 种不同直径的微球栓塞后的底蜕膜动脉血管再通情况(16 头猪,31 条动脉)。在 50-μm 组中,11 条动脉中的 7 条(64%)完全再通,11 条中的 3 条(27%)部分再通,11 条中的 1 条(9%)有侧支循环(无再通)。在 100-300-μm 组中,10 条动脉中的 7 条(70%)完全再通,10 条中的 3 条(30%)部分再通。在 300-500-μm 组中,10 条动脉中的 7 条(70%)完全再通,10 条中的 1 条(10%)部分再通,10 条中的 2 条(20%)有侧支循环。各组之间的再通程度无差异(P=.64)。无论微球大小如何,所有栓塞的动脉都表现出一定程度的血管造影再通。

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本文引用的文献

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Transcatheter Bariatric Embolotherapy for Weight Reduction in Obesity.经导管肥胖症减重栓塞疗法。
J Am Coll Cardiol. 2020 Nov 17;76(20):2305-2317. doi: 10.1016/j.jacc.2020.09.550.
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Gastric Embolization as Treatment for Overweight Patients; Efficacy and Safety.胃栓塞治疗超重患者:疗效与安全性
Cardiovasc Intervent Radiol. 2019 Apr;42(4):513-519. doi: 10.1007/s00270-018-2130-x. Epub 2018 Nov 28.
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Receptivity to Bariatric Surgery in Qualified Patients.符合条件患者对减肥手术的接受度
J Obes. 2016;2016:5372190. doi: 10.1155/2016/5372190. Epub 2016 Jul 19.

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