Department of Nephrology, Dialysis and Internal Diseases, The Medical University of Warsaw, Poland.
Department of Radiology, The Medical University of Warsaw, Poland.
Transplant Proc. 2022 May;54(4):976-980. doi: 10.1016/j.transproceed.2022.03.048. Epub 2022 May 28.
Transplant renal artery stenosis (TRAS) constitutes 75% of all vascular complications in kidney transplant recipients, being a significant source of graft dysfunction and loss. TRAS is a heterogeneous disease with different risk factors and causes. The incidence differs greatly, and it is likely it will increase because of the aging population of potential recipients and donors of renal grafts and the expanding use of extended-criteria donors. Prompt diagnosis and treatment of TRAS can prevent irreversible allograft dysfunction and loss. Current evidence of risk factors, diagnostic challenges, and therapeutic options are presented in this short review.
移植肾动脉狭窄(TRAS)构成了肾移植受者所有血管并发症的 75%,是移植物功能障碍和丧失的重要原因。TRAS 是一种异质性疾病,具有不同的危险因素和病因。其发病率差异很大,由于潜在肾移植受者和供者的人口老龄化以及扩展标准供者的使用增加,其发病率可能会增加。及时诊断和治疗 TRAS 可以预防不可逆的移植物功能障碍和丧失。本综述介绍了目前关于危险因素、诊断挑战和治疗选择的证据。