Orjuela Agustín Góngora, Reyes Castañeda Leidy J, Tobón Julio César, Parra Arango Jorge L, Guzmán-Barragán Blanca
Escuela de Medicina Veterinaria y Zootecnia, Universidad de los Llanos, Villavicencio, Colombia.
Industria Colombiana de Productos Veterinarios (Vecol), Bogotá, Colombia.
Heliyon. 2022 May 18;8(5):e09481. doi: 10.1016/j.heliyon.2022.e09481. eCollection 2022 May.
is a Gram-negative obligate intracellular bacterium, responsible for abortions and reproductive problems. The disease has a high zoonotic potential and causes great economic losses in ruminant farmers. A cross-sectional study was carried out with 514 cattle from 24 farms of Villavicencio, Colombia. The blood samples were collected from each individual animal and analyzed by Indirect Elisa for immunoglobulin G (IgG) in blood serum (Idexx Chlamydiosis total Ab test). A serum was considered positive when the optical density (OD) of the sample was ≥30% of that of the positive control serum. Data on potential risk factors associated with the disease were collected through a questionnaire in each farm and analyzed. The individual and herd prevalence was estimated. A risk factors analysis was performed through univariate and multivariable using the software SPSS version 20. The animal level seroprevalence was found to be 47.1% and the herd 91.6%. The prevalence in cattle aged 0-1, 1-3 and >4 years was 23.8%; 31.4% and 51.4% respectively. The risk factors associated with the prevalence of disease were female sex (OR = 2.102 CI: 1.066-4.144), age older than 4 years (OR = 2.707 CI: 1.667-4.394), presence of canines on the farm (OR = 2.556 CI: 1.560-4.189) and retention of placenta (OR = 2.678 CI: 1.670-4.295). A high prevalence was identified, suggesting natural infection where the pathogen could be transmitted to humans at the animal-human interface.
是一种革兰氏阴性专性细胞内细菌，可导致流产和生殖问题。该疾病具有很高的人畜共患病潜力，给反刍动物养殖户造成巨大经济损失。对来自哥伦比亚比亚维森西奥24个农场的514头牛进行了一项横断面研究。从每头动物采集血样，并通过间接酶联免疫吸附测定法分析血清中的免疫球蛋白G（IgG）（爱德士衣原体病总抗体检测）。当样品的光密度（OD）≥阳性对照血清光密度的30%时，血清被视为阳性。通过在每个农场进行问卷调查收集与该疾病相关的潜在风险因素数据并进行分析。估计了个体和畜群患病率。使用SPSS 20软件通过单变量和多变量进行风险因素分析。发现动物水平的血清阳性率为47.1%，畜群为91.6%。0 - 1岁、1 - 3岁和大于4岁牛的患病率分别为23.8%、31.4%和51.4%。与疾病患病率相关的风险因素为雌性（比值比=2.102，置信区间：1.066 - 4.144）、年龄大于4岁（比值比=2.707，置信区间：1.667 - 4.394）、农场中有犬类（比值比=2.556，置信区间：1.560 - 4.189）和胎盘滞留（比值比=2.678，置信区间：1.670 - 4.295）。确定了高患病率，表明存在自然感染，病原体可能在动物与人类的接触界面传播给人类。
