视网膜动脉阻塞中黄斑中心凹旁急性中层病变与视力预后的关系：一项回顾性队列研究。
Association of Paracentral Acute Middle Maculopathy with Visual Prognosis in Retinal Artery Occlusion: A Retrospective Cohort Study.
作者信息
Liang Siying, Chen Qingshan, Hu Chenli, Chen Miaohong
机构信息
Vitreoretinal Department, Shenzhen Eye Hospital, Shenzhen Eye Institute, Jinan University, Shenzhen 518040, China.
出版信息
J Ophthalmol. 2022 May 21;2022:9404973. doi: 10.1155/2022/9404973. eCollection 2022.
BACKGROUND
The association between paracentral acute middle maculopathy (PAMM) and visual acuity in patients with retinal artery occlusion (RAO) is unknown. This study explored the clinical features and prognostic factors for visual acuity of RAO accompanied by PAMM.
METHODS
This retrospective study included patients with RAO who underwent FFA and OCT examinations at Shenzhen Eye Hospital from July 2015 to June 2019. The changes in vision and macular structure were observed.
RESULTS
Eighty-eight patients were included. There were 58 patients (65.9%) with central RAO (CRAO) and 30 (34.1%) with branch RAO (BRAO). Fifty-two eyes were diagnosed with PAMM, of which 33 eyes (63.5%) were from CRAO patients and 19 (36.5%) were from BRAO patients. At diagnosis, the PAMM group had significantly better logMAR BCVA values than the no-PAMM group (median (IQR), 1.35 (0.725-2) vs. 2.15 (1.47-2.3), =0.002). In addition, the PAMM group had significantly better logMAR BCVA values during follow-up than the no-PAMM group (median (IQR), 1 (0.05-2) vs. 2 (1.15-2.3), =0.001). After adjustment for age, gender, CRAO/BRAO, comorbidities, and symptom duration, PAMM was associated with good visual acuity improvement (RR = 3.29, 95% CI: 1.29-8.37, =0.013).
CONCLUSION
PAMM was associated with good visual acuity improvement during follow-up in patients with RAO.
背景
视网膜中央动脉阻塞（RAO）患者中，黄斑中心凹旁急性黄斑病变（PAMM）与视力之间的关联尚不清楚。本研究探讨了伴有PAMM的RAO患者的临床特征及视力预后因素。
方法
本回顾性研究纳入了2015年7月至2019年6月在深圳眼科医院接受荧光素眼底血管造影（FFA）和光学相干断层扫描（OCT）检查的RAO患者。观察视力和黄斑结构的变化。
结果
共纳入88例患者。其中58例（65.9%）为视网膜中央动脉阻塞（CRAO），30例（34.1%）为视网膜分支动脉阻塞（BRAO）。52只眼被诊断为PAMM，其中33只眼（63.5%）来自CRAO患者，19只眼（36.5%）来自BRAO患者。诊断时，PAMM组的logMAR最佳矫正视力（BCVA）值显著优于非PAMM组（中位数（四分位间距），1.35（0.725 - 2）对2.15（1.47 - 2.3），P = 0.002）。此外，随访期间PAMM组的logMAR BCVA值也显著优于非PAMM组（中位数（四分位间距），1（0.05 - 2）对2（1.15 - 2.3），P = 0.001）。在调整年龄、性别、CRAO/BRAO、合并症和症状持续时间后，PAMM与视力改善良好相关（风险比（RR）= 3.29，95%置信区间（CI）：1.29 - 8.37，P = 0.013）。
结论
在RAO患者的随访中，PAMM与视力改善良好相关。
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