Department of Cardiology, General Hospital of the Yangtze River Shipping, China.
Comput Math Methods Med. 2022 May 21;2022:4305015. doi: 10.1155/2022/4305015. eCollection 2022.
Carotid artery stenosis is one of the most serious diseases that endanger human health in contemporary times. It is a frequently occurring and common disease of the middle-aged and elderly people. Its incidence is increasing year by year, bringing a heavy economic burden to society and families. Whether there is a relationship between the degree of carotid artery stenosis and blood pressure variability is less studied.
To investigate the correlation between the degree of carotid stenosis and blood pressure variability in patients with carotid stenosis.
A total of 200 patients with carotid artery stenosis who were treated in our hospital from January 2017 to January 2020 were selected as the subjects of prospective study and were divided into mild stenosis according to the degree of carotid stenosis (carotid artery stenosis rate was 0-50%), moderate stenosis (carotid artery stenosis rate was between 50% and 70%), severe stenosis (carotid artery stenosis rate≧70%), and the control group with 50 cases each. The correlations between the hemodynamics, the degree of carotid artery stenosis, and blood pressure variability in patients with carotid artery stenosis were analyzed.
The levels of 24hSSD, 24hDSD, dSSD, dDSD, and nSSD in the mild stenosis group and moderate stenosis group were significantly higher than those in the control group. In the stenosis group, the levels of 24hSSD, 24hDSD, dSSD, dDSD, and nSSD in the severe stenosis group were significantly higher than those in the moderate stenosis group, with statistical significance ( < 0.05). The levels of PSV, EDV, and MV in the mild stenosis group and moderate stenosis group were lower than those in the control group, while the PI and RI indexes were higher than those in the control group. PI and RI levels were significantly higher than those in the mild stenosis group and moderate stenosis group ( < 0.05). Logistic analysis showed that EDV ( = 0.001, OR = 2.245, 95%CI = 1.638 ~ 3.078), SSD ( = 0.014, OR = 0.725, 95%CI = 0.528 ~ 0.996), and PSV ( = 0.001, OR = 1.970, 95%CI = 1.300 ~ 2.990) were closely related to the degree of carotid artery stenosis.
Hemodynamics and blood pressure variability are related to the severity of carotid stenosis, which provides a reference and basis for clinical treatment of carotid stenosis.
颈动脉狭窄是当代危害人类健康的最严重疾病之一，是中老年人的多发病、常见病，其发病率呈逐年上升趋势，给社会和家庭带来沉重的经济负担。颈动脉狭窄程度与血压变异性之间是否存在关系研究较少。
探讨颈动脉狭窄患者颈动脉狭窄程度与血压变异性的相关性。
选取 2017 年 1 月至 2020 年 1 月在我院治疗的 200 例颈动脉狭窄患者为前瞻性研究对象，根据颈动脉狭窄程度分为轻度狭窄（颈动脉狭窄率为 0%～50%）、中度狭窄（颈动脉狭窄率为 50%～70%）、重度狭窄（颈动脉狭窄率≧70%），每组各 50 例。分析颈动脉狭窄患者的血流动力学、颈动脉狭窄程度与血压变异性的相关性。
轻度狭窄组和中度狭窄组的 24hSSD、24hDSD、dSSD、dDSD、nSSD 水平明显高于对照组。狭窄组中，重度狭窄组的 24hSSD、24hDSD、dSSD、dDSD、nSSD 水平明显高于中度狭窄组，差异有统计学意义（<0.05）。轻度狭窄组和中度狭窄组的 PSV、EDV、MV 水平低于对照组，PI、RI 指数高于对照组。PI、RI 水平明显高于轻度狭窄组和中度狭窄组（<0.05）。Logistic 分析显示，EDV（=0.001，OR=2.245，95%CI=1.638～3.078）、SSD（=0.014，OR=0.725，95%CI=0.528～0.996）和 PSV（=0.001，OR=1.970，95%CI=1.300～2.990）与颈动脉狭窄程度密切相关。
血流动力学和血压变异性与颈动脉狭窄程度有关，为颈动脉狭窄的临床治疗提供了参考和依据。
