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超声引导下单极与双极射频消融治疗慢性膝骨关节炎疼痛的膝神经:一项随机对照研究。

Ultrasound-guided monopolar versus bipolar radiofrequency ablation for genicular nerves in chronic knee osteoarthritis pain: A randomized controlled study.

作者信息

Elemam Elsayed M, Abdel Dayem Ola T, Mousa Sherif A, Mohammed Hanaa M

机构信息

Department of Anesthesia, Intensive Care and Pain Management, Faculty of Medicine, Mansoura University, Mansoura, Egypt.

出版信息

Ann Med Surg (Lond). 2022 May 2;77:103680. doi: 10.1016/j.amsu.2022.103680. eCollection 2022 May.

DOI:10.1016/j.amsu.2022.103680
PMID:35637984
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9142545/
Abstract

BACKGROUND

This study compared between monopolar and bipolar radiofrequency (RF) ablation of the genicular nerves using ultrasound guidance (USG) in chronic knee osteoarthritis pain.

MATERIAL AND METHODS

This was a prospective, randomized, double-blind study. Fifty patients with knee osteoarthritis pain were equally randomized to either monopolar or bipolar groups. The primary outcome was visual analogue score (VAS). The secondary outcomes were the proportion of successful responders with a reduction of 50% of VAS score at 12 and 24 weeks, the procedure time and pain and oxford knee score (OKS).VAS and OKS were recorded at 1, 4, 12, 24 weeks after intervention. Any complications were reported.

RESULTS

Mean VAS score in bipolar group was (p < 0.05) lower than monopolar group at 12 weeks [4.84 ± 0.62 Vs. 3.56 ± 0.71] and 24 weeks [5.44 ± 0.82 Vs. 3.96 ± 0.79]. The Proportion of successful responders with a reduction of at least 50% of VAS score were more in bipolar group than monopolar group at 12 weeks (80% Vs. 12%) and 24 weeks (44% Vs. 4%). Mean OKS score in bipolar group was (p < 0.05) lower than monopolar group at 12 weeks [26 ± 3 Vs. 34 ± 3] and 24 weeks [27 ± 3 Vs. 35 ± 3].The procedure time and pain were (p < 0.05) lower in monopolar than bipolar group. The complications were similar in both groups.

CONCLUSION

USG bipolar RF ablation is more effective than monopolar RF ablation in controlling knee osteoarthritis pain as for the duration and severity of pain without fluoroscopic confirmation.

摘要

背景

本研究比较了在超声引导(USG)下对慢性膝关节骨关节炎疼痛患者进行单极和双极射频(RF)消融膝神经的效果。

材料与方法

这是一项前瞻性、随机、双盲研究。50例膝关节骨关节炎疼痛患者被平均随机分为单极组或双极组。主要结局指标是视觉模拟评分(VAS)。次要结局指标包括在12周和24周时VAS评分降低50%的成功应答者比例、手术时间、疼痛情况以及牛津膝关节评分(OKS)。在干预后1、4、12、24周记录VAS和OKS。报告任何并发症。

结果

双极组在12周时的平均VAS评分(p<0.05)低于单极组[4.84±0.62对3.56±0.71],在24周时也是如此[5.44±0.82对3.96±0.79]。在12周时,VAS评分降低至少50%的成功应答者比例双极组高于单极组(80%对12%),24周时也是如此(44%对4%)。双极组在12周时的平均OKS评分(p<0.05)低于单极组[26±3对34±3],24周时也是如此[27±3对35±3]。单极组的手术时间和疼痛程度(p<0.05)低于双极组。两组的并发症情况相似。

结论

在无透视确认的情况下,就疼痛持续时间和严重程度而言,超声引导下双极射频消融在控制膝关节骨关节炎疼痛方面比单极射频消融更有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/288b/9142545/07ace3c1d841/gr9.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/288b/9142545/07ace3c1d841/gr9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/288b/9142545/fdf5b8c316b7/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/288b/9142545/1c941c86c973/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/288b/9142545/caf9deeaa95c/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/288b/9142545/647bf6e16f7c/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/288b/9142545/c5e4ed6ea15f/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/288b/9142545/38d0bfafce8c/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/288b/9142545/b9e49cef8702/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/288b/9142545/24de06f88ec7/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/288b/9142545/07ace3c1d841/gr9.jpg

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