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多病症使老年急诊普外科患者面临更大风险,甚于多种合并症的存在:一项回顾性观察研究。

Multimorbidity Confers Greater Risk for Older Patients in Emergency General Surgery Than the Presence of Multiple Comorbidities: A Retrospective Observational Study.

机构信息

Department of Surgery, Hospital of the University of Pennsylvania.

Perelman School of Medicine.

出版信息

Med Care. 2022 Aug 1;60(8):616-622. doi: 10.1097/MLR.0000000000001733. Epub 2022 May 30.

DOI:10.1097/MLR.0000000000001733
PMID:35640050
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9262850/
Abstract

BACKGROUND

Little is known about the impact of multimorbidity on outcomes for older emergency general surgery patients.

OBJECTIVE

The aim was to understand whether having multiple comorbidities confers the same amount of risk as specific combinations of comorbidities (multimorbidity) for a patient undergoing emergency general surgery.

RESEARCH DESIGN

Retrospective observational study using state discharge data.

SUBJECTS

Medicare beneficiaries who underwent an operation for an emergency general surgery condition in New York, Florida, or Pennsylvania (2012-2013).

MEASURES

Patients were classified as multimorbid using Qualifying Comorbidity Sets (QCSs). Outcomes included in-hospital mortality, hospital length of stay and discharge status.

RESULTS

Of 312,160 patients, a large minority (37.4%) were multimorbid. Non-QCS patients did not have a specific combination of comorbidities to satisfy a QCS, but 64.1% of these patients had 3+ comorbid conditions. Multimorbidity was associated with increased in-hospital mortality (10.5% vs. 3.9%, P <0.001), decreased rates of discharge to home (16.2% vs. 37.1%, P <0.001), and longer length of stay (10.4 d±13.5 vs. 6.7 d±9.3, P <0.001) when compared with non-QCS patients. Risks varied between individual QCSs.

CONCLUSIONS

Multimorbidity, defined by satisfying a specific QCS, is strongly associated with poor outcomes for older patients requiring emergency general surgery in the United States. Variation in risk of in-hospital mortality, discharge status, and length of stay between individual QCSs suggests that multimorbidity does not carry the same prognostic weight as having multiple comorbidities-the specifics of which are important in setting expectations for individual, complex patients.

摘要

背景

对于老年急诊普外科患者,合并多种疾病对其预后的影响知之甚少。

目的

旨在了解患有多种合并症(多种合并症)的患者是否与接受急诊普外科手术的患者的特定合并症组合(多种合并症)具有相同的风险。

研究设计

利用州际出院数据进行回顾性观察性研究。

研究对象

2012-2013 年在纽约、佛罗里达州或宾夕法尼亚州接受急诊普外科手术的 Medicare 受益人的手术。

测量指标

采用合并症分类标准(QCS)对患者进行合并症分组。纳入的结局指标包括院内死亡率、住院时间和出院状态。

结果

在 312160 名患者中,少数患者(37.4%)合并多种疾病。非 QCS 患者没有特定的合并症组合符合 QCS,但其中 64.1%的患者有 3 种以上合并症。与非 QCS 患者相比,合并多种疾病的患者的院内死亡率更高(10.5% vs. 3.9%,P <0.001),出院回家的比例更低(16.2% vs. 37.1%,P <0.001),住院时间更长(10.4±13.5 天 vs. 6.7±9.3 天,P <0.001)。个别 QCS 之间的风险存在差异。

结论

通过满足特定 QCS 来定义的多种合并症与美国需要接受急诊普外科手术的老年患者不良预后密切相关。不同 QCS 组之间院内死亡率、出院状态和住院时间风险的差异表明,多种合并症并不像多种合并症那样具有相同的预后权重-对于复杂的个体患者,具体情况很重要。