School of Mathematics and Computer Science, Yunnan Minzu University, Kunming, 650500, PR China.
Key Laboratory of Resource Clean Conversion in Ethnic Regions, Education Department of Yunnan, School of Chemistry and Environment, Yunnan Minzu University, Kunming, 650500, PR China.
Chemosphere. 2022 Sep;303(Pt 2):135145. doi: 10.1016/j.chemosphere.2022.135145. Epub 2022 May 28.
In this study, using a convenient one-pot microwave-assisted method, we rapidly fabricated a N, S-codoped fluorescent carbon dots (NSCDs) through using citric acid (CA) and -penicillamine (DPA) for the detection of tetracyclines (TC). To rapidly and efficiently optimize the various synthesis parameters and significantly decrease the number of experimental runs, the effect of the synthesis factors on quantum yield (QY) by NSCDs was implemented through means of response surface methodology (RSM). The as-synthesized NSCDs presented superior photoluminescence stability with a strong quantum yield (QY) of 91.55% under optimal conditions, which was consistent with the predicted value using RSM. The fluorescence intensity of the NSCDs could be quenched effectively after adding TC by the inner filter effect (IEE) and photoinduced electron transfer (PET). Thus, the determination of TC by using NSCDs as a facile fluorescent probe was constructed in the range of 0.2-70 μM with a limit detection of 0.072 μM. Moreover, this detection approach has been utilized to detect TC in actual samples with satisfactory results.
在这项研究中，我们使用方便的一锅微波辅助法，通过使用柠檬酸（CA）和 - 半胱氨酸（DPA）快速制备了 N，S 共掺杂荧光碳点（NSCDs），用于检测四环素（TC）。为了快速有效地优化各种合成参数，并显著减少实验次数，我们通过响应面法（RSM）研究了合成因素对量子产率（QY）的影响。在最佳条件下，合成的 NSCDs 具有优异的光致发光稳定性，量子产率（QY）高达 91.55%，与 RSM 预测值一致。加入 TC 后，通过内滤效应（IEE）和光诱导电子转移（PET），NSCDs 的荧光强度可以被有效猝灭。因此，我们构建了一种基于 NSCDs 的简便荧光探针来测定 TC，其测定范围为 0.2-70 μM，检测限为 0.072 μM。此外，该检测方法已用于实际样品中 TC 的检测，结果令人满意。
