多学科肿瘤委员会对组织细胞疾病患者治疗的影响：组织细胞疾病工作组的经验。
Impact of a Multidisciplinary Tumor Board on the Care of Patients with Histiocytic Disorders: The Histiocytosis Working Group experience.
机构信息
Division of Hematology-Oncology, University of Alabama at Birmingham, Birmingham, AL, USA.
Division of Hematology, Mayo Clinic, Rochester, MN, USA.
出版信息
Oncologist. 2022 Mar 4;27(2):144-148. doi: 10.1093/oncolo/oyab031.
INTRODUCTION
Histiocytic disorders pose significant diagnostic and management challenges for the clinicians due to diverse clinical manifestations and often non-specific histopathologic findings. Herein, we report the tumor board experience from the first-of-its-kind Histiocytosis Working Group (HWG).
MATERIALS AND METHODS
The HWG was established in June 2017 and consists of experts from 10 subspecialties that discuss cases in a multidisciplinary format. We present the outcome of tumor board case discussions during the first 2 years since its inception (June 2017-June 2019).
RESULTS
Forty cases with a suspected histiocytic disorder were reviewed at HWG during this time period. Average number of subspecialties involved in HWG case discussion was 5 (range, 2-9). Histiocytosis Working Group tumor board recommendations led to significant changes in the care of 24 (60%) patients. These included change in diagnosis (n = 11, 27%) and change in treatment (n = 13, 33%).
CONCLUSION
Our report highlights the feasibility of a multidisciplinary tumor board and its impact on outcomes of patients with histiocytic disorders.
简介
由于临床表现多样且组织病理学表现常不具有特异性，组织细胞疾病给临床医生带来了重大的诊断和治疗挑战。在此，我们报告首例组织细胞疾病工作组（HWG）的肿瘤委员会经验。
材料与方法
HWG 于 2017 年 6 月成立，由 10 个亚专业的专家组成，以多学科的形式讨论病例。我们介绍自成立以来（2017 年 6 月至 2019 年 6 月）HWG 肿瘤委员会讨论的前 2 年的病例讨论结果。
结果
在此期间，HWG 共对 40 例疑似组织细胞疾病的患者进行了审查。HWG 病例讨论平均涉及 5 个（范围为 2-9）亚专业。组织细胞疾病工作组肿瘤委员会的建议显著改变了 24 例（60%）患者的治疗方案。其中包括诊断的改变（11 例，27%）和治疗的改变（13 例，33%）。
结论
我们的报告强调了多学科肿瘤委员会的可行性及其对组织细胞疾病患者结局的影响。
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