Department of Pediatry, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation.
Department of Medicine, Lake Erie College of Osteopathic Medicine (LECOM), Erie, PA, USA.
Hipertens Riesgo Vasc. 2022 Oct-Dec;39(4):157-166. doi: 10.1016/j.hipert.2022.04.001. Epub 2022 May 28.
Arterial hypertension (AH) is one of the key risk factors and triggers for the development of acute cerebrovascular accident. The purpose of the study is to investigate the peculiarities and rates of blood pressure reduction in AH patients during the acute period of ischemic stroke depending on the patients' sex, age, medical history, and clinical characteristics.
The study involved 120 patients aged 41-77 years, of whom there were 47 (39.2%) men and 73 (60.8%) women. All enrolled patients had established diagnoses of AH and acute ischemic cerebrovascular accident (acute ischemic stroke, AIS), with the latter diagnosed within the first 24h from onset. The follow-up period was 14 days.
An increase in diastolic blood pressure was associated with higher scores on the National Institutes of Health Stroke Scale (NIHSS, r=0.301, p=0.026) and Rankin scale (r=0.225, p=0.030), as well as a worse health status at the time of discharge from hospital (r=0.318, p=0.021).
Diastolic blood pressure can be considered a marker of the severity of neurological disorders in AIS, which should be considered when monitoring such patients.
动脉高血压（AH）是急性脑血管意外发展的关键风险因素和触发因素之一。本研究旨在探讨急性缺血性卒中患者在急性发作期间，根据患者的性别、年龄、病史和临床特征，AH 患者血压降低的特点和速度。
本研究纳入了 120 名年龄在 41-77 岁的患者，其中男性 47 例（39.2%），女性 73 例（60.8%）。所有入组患者均确诊为 AH 和急性缺血性脑血管病（急性缺血性卒中，AIS），后者在发病后 24 小时内确诊。随访期为 14 天。
舒张压升高与 NIHSS 评分（r=0.301，p=0.026）和 Rankin 量表评分（r=0.225，p=0.030）呈正相关，与出院时的健康状况呈负相关（r=0.318，p=0.021）。
舒张压可作为 AIS 神经功能障碍严重程度的标志物，在监测此类患者时应予以考虑。
