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人工关节置换术的肘部使用寿命有多长?一项超过 10 年随访的病例系列和国家登记报告的系统回顾和荟萃分析。

How long does an elbow replacement last? A systematic review and meta-analysis of case-series and national registry reports with more than 10 years of follow-up.

机构信息

Health & Policy Research Group, University of Exeter, Exeter; National Institute for Health Research Applied Research Collaboration South West Peninsula, University of Exeter, Exeter.

Musculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, 1st Floor Learning & Research Building, Southmead Hospital, Bristol.

出版信息

Acta Orthop. 2022 May 31;93:495-502. doi: 10.2340/17453674.2022.2753.

Abstract

BACKGROUND AND PURPOSE

This study aims to determine, for the first time, generalizable data on the longevity and long-term function of elbow replacements.

METHODS

In this systematic review and meta-analysis, we searched MEDLINE and Embase for articles reporting 10-year or greater survival of total elbow replacements (TERs) and distal humeral hemiarthroplasty. Implant survival and patient reported outcome measures (PROMs) data were extracted. National joint replacement registries were also analyzed. We weighted each series and calculated a pooled survival estimate at 10, 15, and 20 years. For PROMs we pooled the standardized mean difference (SMD) at 10 years.

FINDINGS

Despite its widespread use, we identified only 9 series reporting all-cause survival of 628 linked TERs and 610 unlinked TERs and no series for distal humeral hemiarthroplasty. The studied population was treated for rheumatoid arthritis in over 90% of cases. The estimated 10-year survival for linked TERs was 92% (95% CI 90-95) and unlinked TERs 84% (CI 81-88). 2 independent registries contributed 32 linked TERs and 530 unlinked TERs. The pooled registry 10-year survival for unlinked TERs was 86% (CI 83-89). Pooled 10-year PROMs from 164 TERs (33 linked and 131 unlinked), revealed a substantial improvement from baseline scores (SMD 2.7 [CI 1.6-3.8]).

INTERPRETATION

Over 80% of all elbow replacements and over 90% of linked elbow replacements can last more than 10 years with sustained patient-reported benefits. This information is long overdue and will be particularly useful to patients as well as healthcare providers.

摘要

背景与目的

本研究旨在首次确定肘部置换的长期生存率和长期功能的可推广数据。

方法

在这项系统评价和荟萃分析中,我们检索了 MEDLINE 和 Embase 中报告全肘置换(TER)和肱骨远端半关节置换 10 年或以上生存率的文章。提取了植入物生存率和患者报告的结果测量(PROM)数据。还分析了国家关节置换登记处。我们对每个系列进行加权,并计算 10 年、15 年和 20 年的 pooled survival estimate。对于 PROM,我们在 10 年时汇集了标准化均数差(SMD)。

发现

尽管肘部置换术广泛应用,但我们仅发现 9 个系列报告了 628 个链接 TER 和 610 个非链接 TER 的全因生存率,没有远端肱骨半关节置换术的系列报告。研究人群中超过 90%的病例因类风湿性关节炎接受治疗。链接 TER 的 10 年生存率估计为 92%(95%CI 90-95),非链接 TER 为 84%(CI 81-88)。2 个独立的登记处分别贡献了 32 个链接 TER 和 530 个非链接 TER。非链接 TER 的汇总登记处 10 年生存率为 86%(CI 83-89)。来自 164 个 TER(33 个链接和 131 个非链接)的汇总 10 年 PROM 显示,与基线评分相比有显著改善(SMD 2.7[CI 1.6-3.8])。

解释

超过 80%的肘部置换术和超过 90%的链接肘部置换术可以持续 10 年以上,同时患者报告的获益持续存在。这一信息已经滞后太久,对患者和医疗保健提供者都将特别有用。

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