苏丹东部 2 型糖尿病男性勃起功能障碍的患病率及相关因素。
Prevalence and associated factors of erectile dysfunction in men with type 2 diabetes mellitus in eastern Sudan.
机构信息
Faculty of Medicine and Health Science, Gadarif University, Gadarif, Sudan.
Royal Commission Hospital at AL Jubail Industrial City, Al Jubail, Kingdom of Saudi Arabia.
出版信息
BMC Endocr Disord. 2022 May 28;22(1):141. doi: 10.1186/s12902-022-01060-0.
BACKGROUND
Diabetes mellitus (DM) is a global health threat and burden that is associated with many chronic complications. Erectile dysfunction (ED) among patients with DM is one of these complications. There is no published data on ED in Sudan; hence, we conducted this study to evaluate the prevalence of ED and the associated factors in patients with type 2 diabetes mellitus (T2DM) in eastern Sudan.
METHODS
We performed a cross-sectional study. Data on blood glucose level, cholesterol level, anthropometric and demographic characteristics, results of the International Index of Erectile Function (IIEF-5) questionnaire, and clinical history were obtained.
RESULTS
A total of 334 men with T2DM with a median (interquartile range [IQR]) age of 55.0 (±10.0) years were enrolled in the study. The median (IQR) of the duration of DM was 7.0 (±8) years, and 260 (77.8%) had uncontrolled T2DM. The median (IQR) body mass index was 24.5 (±4.9) kg/m. Of the participants, 81 (24.3%) had severe ED, 52 (15.6%) had moderate ED, 75 (22.5%) had mild to moderate ED, and 63 (13.9%) had mild ED. Of the 334 men, 271 (81.1%) had ED. Logistic regression analysis showed that age (adjusted Odds Ratio [AOR] = 1.07, 95% confidence interval [CI] = 1.01-1.14), duration of DM (AOR = 1.26, 95% CI = 1.06-1.51), and cholesterol levels (AOR = 3.53, 95% CI = 1.75-7.11) were positively associated with ED. Moreover, poor glycaemic control (AOR = 3.38, 95% CI = 1.70-6.71, P < 0.001) was significantly associated with ED.
CONCLUSION
There is a high prevalence of ED among patients with T2DM in eastern Sudan. Age, duration of DM, and cholesterol were positively associated with ED.
背景
糖尿病（DM）是一种全球健康威胁和负担，与许多慢性并发症有关。DM 患者的勃起功能障碍（ED）就是其中一种并发症。苏丹没有关于 ED 的发表数据；因此，我们进行了这项研究，以评估在苏丹东部 2 型糖尿病（T2DM）患者中 ED 的患病率和相关因素。
方法
我们进行了一项横断面研究。获得了血糖水平、胆固醇水平、人体测量和人口统计学特征、国际勃起功能指数（IIEF-5）问卷的结果以及临床病史的数据。
结果
共纳入 334 名 T2DM 男性，年龄中位数（四分位距 [IQR]）为 55.0（±10.0）岁。DM 的中位（IQR）病程为 7.0（±8）年，260 名（77.8%）患者的 T2DM 未得到控制。参与者的中位（IQR）体重指数为 24.5（±4.9）kg/m。其中，81 名（24.3%）患者有严重 ED，52 名（15.6%）患者有中度 ED，75 名（22.5%）患者有轻度至中度 ED，63 名（13.9%）患者有轻度 ED。334 名男性中有 271 名（81.1%）有 ED。逻辑回归分析显示，年龄（调整后优势比 [AOR] = 1.07，95%置信区间 [CI] = 1.01-1.14）、DM 病程（AOR = 1.26，95% CI = 1.06-1.51）和胆固醇水平（AOR = 3.53，95% CI = 1.75-7.11）与 ED 呈正相关。此外，血糖控制不佳（AOR = 3.38，95% CI = 1.70-6.71，P < 0.001）与 ED 显著相关。
结论
苏丹东部 T2DM 患者 ED 的患病率较高。年龄、DM 病程和胆固醇与 ED 呈正相关。
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