Abdlshikure Seid Abrar, Mamo Aklilu Getachew, Fikadu Bisrat, Seid Abdulber
Department of Medical Laboratory Sciences, College of Medicine and Health Sciences, Wolkite University, Wolkite, Ethiopia.
School of Medical Laboratory Science, Faculty of Health Sciences, Institute of Health, Jimma University, Jimma, Ethiopia.
PLoS One. 2025 Apr 21;20(4):e0318908. doi: 10.1371/journal.pone.0318908. eCollection 2025.
Erectile dysfunction (ED) is often not recognized in men with type 2 diabetes mellitus (T2DM), despite the prevalence of the disease. Early diagnosis of ED in T2DM is very important for effective treatment and prevention of serious complications such as cardiovascular events.This study investigates the prevalence and determinants of ED among T2DM patients at selected government hospitals in the Gurage Zone.
We conducted a study in three public hospitals from September 1 to December 30, 2020. 204 diabetic men were selected using consecutive sampling. ED was evaluated utilizing the International Index of ED-5. Glycated hemoglobin (HbA1c) and lipid levels were analyzed utilizing a Cobas 600 clinical chemistry analyzer. The data was analyzed using the Statistical Package for Social Sciences-20.
ED was observed in 156 (76.5%) diabetic males. Independent predictors of ED included age above 40 years, alcohol consumption, khat chewing, overweight [Body mass index (BMI) ≥ 25 kg/m2], obesity (BMI ≥ 30 kg/m2), a diabetes duration of more than 5 years, uncontrolled diabetes (HbA1c > 7%), elevated low-density lipoprotein (LDL), and high total cholesterol levels (P < 0.05).
The study confirmed a high prevalence of ED among males with T2DM in the study settings. Consequently, clinicians should adopt preventive measures and focus on identifying the factors associated with ED in these patients.
尽管2型糖尿病（T2DM）患病率较高，但男性T2DM患者中的勃起功能障碍（ED）往往未被识别。T2DM患者中ED的早期诊断对于有效治疗和预防心血管事件等严重并发症非常重要。本研究调查了古拉格地区选定政府医院中T2DM患者ED的患病率及其决定因素。
我们于2020年9月1日至12月31日在三家公立医院开展了一项研究。采用连续抽样法选取了204名男性糖尿病患者。使用国际勃起功能障碍指数-5评估ED。利用Cobas 600临床化学分析仪分析糖化血红蛋白（HbA1c）和血脂水平。使用社会科学统计软件包-20对数据进行分析。
156名（76.5%）男性糖尿病患者存在ED。ED的独立预测因素包括年龄40岁以上、饮酒、咀嚼巧茶、超重[体重指数（BMI）≥25kg/m²]、肥胖（BMI≥30kg/m²）、糖尿病病程超过5年、糖尿病控制不佳（HbA1c>7%）、低密度脂蛋白（LDL）升高和总胆固醇水平高（P<0.05）。
该研究证实了研究环境中男性T2DM患者ED的高患病率。因此，临床医生应采取预防措施，并专注于识别这些患者中与ED相关的因素。
