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三尖瓣修复与置换治疗孤立性三尖瓣感染性心内膜炎的结局相似。

Similar outcome of tricuspid valve repair and replacement for isolated tricuspid infective endocarditis.

机构信息

Cardio-Thoracic Surgery Department, Heart & Vascular Centre, Maastricht University Medical Centre, Maastricht, The Netherlands.

Cardiac Surgery, Centro Cardiologico Monzino, Milan.

出版信息

J Cardiovasc Med (Hagerstown). 2022 Jun 1;23(6):406-413. doi: 10.2459/JCM.0000000000001310.

Abstract

AIMS

To compare early and late mortality of acute isolated tricuspid valve infective endocarditis (TVIE) treated with valve repair or replacement.

METHODS

Patients who were surgically treated for TVIE from 1983 to 2018 were retrieved from the Italian Registry for Surgical Treatment of Valve and Prosthesis Infective Endocarditis. All the patients were followed up by means of phone interview or calling patient referral physicians or cardiologists. Kaplan-Meier method was used to assess late survival and survival free from TVIE recurrence with log-rank test for univariate comparison. The primary end points were early mortality (30 days after surgery) and long-term survival free from TVIE recurrence.

RESULTS

A total of 4084 patients were included in the registry. Among them, 149 patients were included in the study. Overall, 77 (51.7%) underwent TV repair and 72 (48.3%) TV replacement. Early mortality was 9% (13 patients). Expected early mortality according to EndoSCORE was 12%. The TV repair showed lower mortality and major complication rate (7% and 16%), compared with TV replacement (11% and 25%), but statistical significance was not reached. Median follow-up was 19.1 years (14.3-23.8). Late deaths were 30 and IE recurrences were 5. No difference in cardiac survival free from IE was found between the two groups after 20 years (80 ± 6% Repair Group vs 59 ± 13% Replacement Group, P = 0.3).

CONCLUSIONS

Overall results indicate that once surgically addressed, TVIE has a low recurrence rate and excellent survival, apparently regardless of the type of surgery used to treat it.

摘要

目的

比较经手术修复或置换治疗急性孤立性三尖瓣感染性心内膜炎(TVIE)的早期和晚期死亡率。

方法

从意大利外科治疗瓣膜和人工瓣膜感染性心内膜炎登记处中检索了 1983 年至 2018 年期间接受 TVIE 手术治疗的患者。所有患者均通过电话访谈、联系患者转诊医生或心脏病专家进行随访。Kaplan-Meier 法用于评估晚期生存率和无 TVIE 复发的生存率,对数秩检验用于单因素比较。主要终点为早期死亡率(手术后 30 天)和无 TVIE 复发的长期生存率。

结果

该登记处共纳入 4084 例患者,其中 149 例患者纳入研究。总体而言,77 例(51.7%)接受了 TV 修复,72 例(48.3%)接受了 TV 置换。早期死亡率为 9%(13 例)。根据 EndoSCORE 预测的早期死亡率为 12%。与 TV 置换相比,TV 修复的死亡率和主要并发症发生率较低(分别为 7%和 16%),但差异无统计学意义。中位随访时间为 19.1 年(14.3-23.8 年)。晚期死亡 30 例,IE 复发 5 例。两组患者在 20 年后无 IE 生存的心脏生存率无差异(修复组 80±6% vs 置换组 59±13%,P=0.3)。

结论

总体结果表明,TVIE 一旦手术治疗,复发率低,生存率高,明显与手术方式无关。

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