Department of Radiotherapy, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Shandong Province, China.
Department of Radiotherapy, Qilu Hospital of Shandong University, Jinan, China.
J Cancer Res Ther. 2022 Apr;18(2):432-437. doi: 10.4103/jcrt.jcrt_65_22.
To study whether an interactive improved internal feedback system with the model can be established, we compared the plans generated by two automatic planning models.
Seventy cases of pelvic patients were selected. Intensity-modulated radiation therapy (IMRT) plans (P0) generated by the clinical model (M0) were imported into the Rapid plan model to establish a dose-volume histogram. The predicted model through automatic planning model in clinical, and the new rapid plan model (M1) was generated by training and structure matching settings. The 70 new IMRT plans (P1) were generated by M1, and the new rapid plan model (M2) was trained by P1. In this same method, 70 IMRT plans (P2) were generated by M2. Dosimetric differences between P1 and P2 were then compared and analyzed.
For the model parameters, R and X in P2 were higher than those in P1, and the CD values of the bladder, right femoral head, and rectum in P1 were higher than those of corresponding organs in P2. The studentized residual (SR) value of the bladder and SR and difference of estimate values of the left femoral head and right femoral head in P1 were lower than P2. In planning, (D, D, and HI) P1 were better than P2 (P < 0.01); the bladder V10 and left femoral head V40 in P2 were lower than in P1 by 0.08% and 0.15%, respectively (P < 0.05); others in P2 were higher than those in P1 (P < 0.05) except the bladder V20, D, rectum V10, V20, V30, right femoral head V10, and V40; and the MUs of P2 was lower than that of P1 for 132.2 (P < 0.05).
The stability of M2 is stronger than that of M1. Therefore, the interactive improved internal feedback system within the model of "plan-model-plan-model" is feasible and meaningful.
为了研究是否可以建立一个具有模型的交互式改进内部反馈系统，我们比较了两个自动规划模型生成的计划。
选择 70 例骨盆患者。将临床模型（M0）生成的调强放疗（IMRT）计划（P0）导入 Rapid 计划模型以建立剂量-体积直方图。通过临床自动规划模型预测模型，并通过训练和结构匹配设置生成新的快速计划模型（M1）。通过 M1 生成 70 个新的 IMRT 计划（P1），然后通过 P1 训练新的快速计划模型（M2）。以同样的方法，由 M2 生成 70 个 IMRT 计划（P2）。然后比较和分析 P1 和 P2 之间的剂量差异。
对于模型参数，P2 中的 R 和 X 高于 P1，P1 中膀胱、右股骨头和直肠的 CD 值高于 P2。P1 中膀胱和左股骨头和右股骨头的标准化残差（SR）值低于 P2。在计划方面，（D、D 和 HI）P1 优于 P2（P<0.01）；P2 中膀胱 V10 和左股骨头 V40 分别比 P1 低 0.08%和 0.15%（P<0.05）；P2 中其他参数高于 P1（P<0.05），除了膀胱 V20、D、直肠 V10、V20、V30、右股骨头 V10 和 V40；P2 的 MU 比 P1 低 132.2（P<0.05）。
M2 的稳定性强于 M1。因此，“计划-模型-计划-模型”模型内的交互式改进内部反馈系统是可行且有意义的。
