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新型冠状病毒2型感染期间的菌血症:病例报告、文献综述及临床思考

Bacteremia during SARS-CoV2 Infection: Case Report, Literature Review, and Clinical Considerations.

作者信息

Marino Andrea, Campanella Edoardo, Stracquadanio Stefano, Ceccarelli Manuela, Zagami Aldo, Nunnari Giuseppe, Cacopardo Bruno

机构信息

Department of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy.

Department of Clinical and Experimental Medicine, Unit of Infectious Diseases, ARNAS Garibaldi Hospital, University of Catania, 95122 Catani, Italy.

出版信息

Infect Dis Rep. 2022 May 12;14(3):383-390. doi: 10.3390/idr14030042.

DOI:10.3390/idr14030042
PMID:35645221
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9149851/
Abstract

Bacterial infections, especially those in hospital settings, represent a major complication of COVID-19 patients, complicating management and worsening clinical outcomes. is a non-diphtheric actinobacterium that has been reported as being the causative agent of several different infections, affecting both immunocompetent and immunocompromised patients. Recently, has been recognized as a nosocomial pathogen that is responsible for severe infection in critical patients, as well as in fragile and immunocompromised subjects. has been described as the etiological agent of bacteremia, central line infections, and endocarditis. We report a case of a 91-year-old woman who was hospitalized due to SARS-CoV-2 infection, who developed bacteremia and died despite antimicrobial therapy and clinical efforts. Furthermore, we discuss diagnosis and treatment based on evidence from the scientific literature.

摘要

细菌感染,尤其是医院环境中的感染,是新冠肺炎患者的主要并发症,使治疗复杂化并恶化临床结果。[具体细菌名称]是一种非白喉放线菌,已被报道为几种不同感染的病原体,可影响免疫功能正常和免疫功能低下的患者。最近,[具体细菌名称]已被确认为一种医院病原体,可导致重症患者以及脆弱和免疫功能低下的受试者发生严重感染。[具体细菌名称]已被描述为菌血症、中心静脉导管相关感染和心内膜炎的病原体。我们报告了一例91岁女性因感染新型冠状病毒住院,发生了[具体细菌名称]菌血症,尽管进行了抗菌治疗和临床努力仍死亡的病例。此外,我们根据科学文献中的证据讨论了[具体细菌名称]的诊断和治疗。

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