Department of General Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, China.
Department of Endocrinology, Affiliated Dalian Municipal Friendship Hospital of Dalian Medical University, Dalian 116001, Liaoning Province, China.
World J Gastroenterol. 2022 Apr 7;28(13):1329-1337. doi: 10.3748/wjg.v28.i13.1329.
Small intestine disease endangers human health and is not easy to locate and diagnose.
To observe the effect of the MS series of small intestine endoscopes on the gastrointestinal tract, the changes in serum gastrin levels and intestinal tissue, and the time required for the examination.
experiments in 20 Living pigs were conducted, Bowel preparation was routinely performed, Intravenous anesthesia with propofol and ketamine was applied, the condition of the small intestine was observed and the detection time of the MS series of small intestine endoscopes were recorded, The changes in intestinal tissue using the MS series of small intestine endoscopes observed and compared before and after the examination, Venous blood (3-5 mL) from pigs was collected before and after the experiment; changes in intestinal tissue after use of the MS series of small intestine endoscopes observed after examination. After completion of each type of small intestine endoscope experiment, the pigs were allowed to rest and the next type of small intestine endoscope experiment was performed after 15 days of normal feeding. The detection time data of the single-balloon small intestine endoscope and double-balloon small intestine endoscope were collected from four hospitals.
One case of , one of suspected Crohn's disease, one small intestinal diverticulum and one anesthesia accident were observed in pigs. The small intestine showed no differences in the MS series of small intestine endoscopes and there were no differences in serum gastrin between the groups ( > 0.05). The time required for inspection was recorded, and the overall detection time for the Japanese small intestine endoscopes was approximately 1.68 ± 0.16 h.
Intestinal ascariasis is a common disease in pigs. Some pigs have abnormal intestinal variation. After continuous upgrade and improvement, the MS-3 and MS-4 small intestine endoscope appear superior in terms of detection time.
小肠疾病危害人类健康，且不易定位和诊断。
观察 MS 系列小肠镜对胃肠道、血清胃泌素水平和肠组织的变化及检查所需时间。
对 20 头活体猪进行实验，常规肠道准备，异丙酚和氯胺酮静脉麻醉，观察小肠情况并记录 MS 系列小肠镜的检查时间，观察并比较使用 MS 系列小肠镜前后肠组织的变化，在实验前后采集每头猪静脉血（3-5ml）；观察检查后 MS 系列小肠镜使用后的肠组织变化。每次完成一种小肠镜检查后，让猪休息 15 天正常喂养后再进行下一种小肠镜检查。从四家医院收集单气囊小肠镜和双气囊小肠镜的检测时间数据。
在猪中观察到 1 例疑似克罗恩病，1 例小肠憩室和 1 例麻醉事故。MS 系列小肠镜下小肠无差异，各组间血清胃泌素无差异（>0.05）。记录检查所需时间，日本小肠镜的总体检查时间约为 1.68±0.16h。
肠蛔虫病是猪的常见病，部分猪有异常的肠变异。经过不断的升级和改进，MS-3 和 MS-4 小肠镜在检查时间上表现出优势。
