Wojas Oksana, Szczêsnowicz-Dąbrowska Paulina, Krzych-Fałta Edyta, Samel-Kowalik Piotr, Samoliński Bolesław, Grzanka Antoni
Department of the Environmental Hazards Prevention and Allergology, Faculty of Health Sciences, Medical University of Warsaw, Warsaw, Poland.
Postepy Dermatol Alergol. 2022 Apr;39(2):347-352. doi: 10.5114/ada.2021.105361. Epub 2021 Apr 18.
A specific difficulty in the standardization of nasal allergen challenge tests as measured by acoustic rhinometry is the lack of reference values measured according to dependent changes, for example height and weight/height- or weight-dependent changes. Human growth and development rates and other changes the human body undergoes throughout the lifetime depend closely on the environment, sex, and race.
To assess selected anthropometric (body weight and height) and rhinometric (nasal cross-sectional areas) measurements concerning subject age and sex.
The study was conducted in 633 subjects selected in multistage, stratified sampling (324 females and 309 males). Body weight and height were measured with a sliding weight scale and height measure. Nasal cavity cross-sectional areas were measured via acoustic rhinometry.
We observed parallel increases in the evaluated anthropometric measurements and nasal cavity cross-sectional areas both in males and females aged ≤ 14 years, with the two sexes starting to differ significantly in terms of those measurements over the age of 14 ( < 0.0001; < 0.000001). The evaluated rhinometric measurements showed a greater correlation with height than with body weight. The time of the most diversified and dynamic changes in anthropomorphic measurements was the age of > 12 years: with boys demonstrating significantly higher mean values of height and body weight than girls.
Height showed a better correlation with rhinometric measurements (cross-sectional area of the nasal cavity) in younger subjects (at their age of development) than in older ones.
通过鼻声反射测量法对鼻过敏原激发试验进行标准化时，一个特殊的困难在于缺乏根据相关变化（例如身高、体重/身高或体重相关变化）测量的参考值。人类的生长发育速度以及人体在一生中经历的其他变化，都与环境、性别和种族密切相关。
评估与受试者年龄和性别相关的选定人体测量学（体重和身高）和鼻测量学（鼻腔横截面积）指标。
本研究采用多阶段分层抽样法选取了633名受试者（324名女性和309名男性）。使用滑动秤和身高测量仪测量体重和身高。通过鼻声反射测量法测量鼻腔横截面积。
我们观察到，在14岁及以下的男性和女性中，所评估的人体测量指标和鼻腔横截面积均呈平行增加，14岁以上时，两性在这些指标上开始出现显著差异（<0.0001；<0.000001）。所评估的鼻测量指标与身高的相关性高于与体重的相关性。人体测量指标变化最多样化和最活跃的时期是12岁以上：男孩的身高和体重平均值显著高于女孩。
在较年轻的受试者（处于发育年龄）中，身高与鼻测量指标（鼻腔横截面积）的相关性优于年龄较大的受试者。
