Law Mikaela, Jarrett Paul, Nieuwoudt Michel K, Holtkamp Hannah, Giglio Cannon, Broadbent Elizabeth
Department of Psychological Medicine, The University of Auckland, Auckland, New Zealand.
Department of Dermatology, Middlemore Hospital, Auckland, New Zealand.
Front Psychol. 2022 May 12;13:871295. doi: 10.3389/fpsyg.2022.871295. eCollection 2022.
Stress can play a role in the onset and exacerbation of psoriasis. Psychological interventions to reduce stress have been shown to improve psychological and psoriasis-related outcomes. This pilot randomised study investigated the feasibility of a brief interaction with a Paro robot to reduce stress and improve skin parameters, after a stressor, in patients with psoriasis.
Around 25 patients with psoriasis participated in a laboratory stress task, before being randomised to either interact with a Paro robot or sit quietly (control condition) for 30 min. Raman spectroscopy and trans-epidermal water loss were measured at baseline, after the stressor and after the intervention as indexes of acute skin changes. Psychological variables, including self-reported stress and affect, were also measured at the three time-points.
No statistically significant differences between the two conditions were found for any of the outcomes measured. However, effect sizes suggest significance could be possible with a larger sample size. Changes in the psychological and Raman spectroscopy outcomes across the experimental session were found, indicating the feasibility of the procedures.
This pilot study showed that a brief interaction with a Paro robot was a feasible intervention for patients with psoriasis, but future trials should broaden the inclusion criteria to try to increase recruitment rates. Studying people who are highly stressed, depressed or who are stress-responders may increase the power of the intervention to show effects using a longer-term intervention.
压力可能在银屑病的发病和加重过程中起作用。已证明减轻压力的心理干预可改善心理及与银屑病相关的结果。这项初步随机研究调查了在银屑病患者经历应激源后,与帕罗机器人进行简短互动以减轻压力并改善皮肤参数的可行性。
约25名银屑病患者参与一项实验室应激任务,之后被随机分为两组,一组与帕罗机器人互动30分钟,另一组安静坐着(对照条件)。在基线、应激源后及干预后测量拉曼光谱和经表皮水分流失,作为急性皮肤变化的指标。在这三个时间点还测量了包括自我报告的压力和情感等心理变量。
在测量的任何结果中,两组之间均未发现统计学上的显著差异。然而,效应量表明样本量更大时可能具有显著性。在整个实验过程中发现了心理和拉曼光谱结果的变化,表明该程序具有可行性。
这项初步研究表明,与帕罗机器人进行简短互动对银屑病患者是一种可行的干预措施,但未来试验应拓宽纳入标准以提高招募率。研究压力大、抑郁或对应激有反应的人群,可能会增强干预效果的显示能力,采用长期干预措施。