Division of Pharmacy and Optometry, University of Manchester, Manchester, UK
Division of Informatics, Imaging & Data Sciences, University of Manchester, Manchester, UK.
BMJ. 2020 May 28;369:m1590. doi: 10.1136/bmj.m1590.
To systematically review and provide information on the incidence of psoriasis and quantify global, regional, and country specific estimates of its prevalence.
Systematic review and meta-analysis.
Medline, Embase, Web of Science, SciELO, Korean Journal Databases, Russian Science Citation Index, WPRIM, SaudiMedLit, Informit, IndMed, and HERDIN were searched systematically from their inception dates to October 2019.
Studies were included if they reported on the incidence or prevalence of psoriasis in the general population. Incidence data were summarised descriptively, whereas bayesian hierarchical models were fitted to estimate the global, regional, and country specific prevalence of psoriasis.
41 164 records were identified and 168 studies met the inclusion criteria. In adults, the incidence of psoriasis varied from 30.3 per 100 000 person years (95% confidence interval 26.6 to 34.1) in Taiwan to 321.0 per 100 000 person years in Italy. The prevalence of psoriasis varied from 0.14% (95% uncertainty interval 0.05% to 0.40%) in east Asia to 1.99% (0.64% to 6.60%) in Australasia. The prevalence of psoriasis was also high in western Europe (1.92%, 1.07% to 3.46%), central Europe (1.83%, 0.62% to 5.32%), North America (1.50%, 0.63% to 3.60%), and high income southern Latin America (1.10%, 0.36% to 2.96%).
Eighty one per cent of the countries of the world lack information on the epidemiology of psoriasis. The disease occurs more frequently in adults than in children. Psoriasis is unequally distributed across geographical regions; it is more frequent in high income countries and in regions with older populations. The estimates provided can help guide countries and the international community when making public health decisions on the appropriate management of psoriasis and assessing its natural history over time.
PROSPERO CRD42019160817.
系统回顾并提供有关银屑病发病率的信息，并量化其全球、区域和国家特定患病率的估计值。
系统回顾和荟萃分析。
从成立日期起，通过 Medline、Embase、Web of Science、SciELO、韩国期刊数据库、俄罗斯科学引文索引、WPRIM、沙特医学文献、Informit、IndMed 和 HERDIN 系统地搜索了 Medline、Embase、Web of Science、SciELO、韩国期刊数据库、俄罗斯科学引文索引、WPRIM、沙特医学文献、Informit、IndMed 和 HERDIN。
如果研究报告了普通人群中银屑病的发病率或患病率，则将其纳入研究。发病率数据以描述性方式进行总结，而贝叶斯层次模型则用于估计银屑病的全球、区域和国家特定患病率。
共确定了 4164 条记录，有 168 项研究符合纳入标准。在成年人中，银屑病的发病率从台湾的每 10 万人 30.3 例（95%置信区间 26.6 至 34.1）到意大利的每 10 万人 321.0 例不等。银屑病的患病率从东亚的 0.14%（95%不确定区间 0.05%至 0.40%）到澳大拉西亚的 1.99%（0.64%至 6.60%）不等。西欧（1.92%，1.07%至 3.46%）、中欧（1.83%，0.62%至 5.32%）、北美（1.50%，0.63%至 3.60%）和高收入南拉丁美洲（1.10%，0.36%至 2.96%）的银屑病患病率也很高。
世界上 81%的国家缺乏银屑病流行病学信息。这种疾病在成年人中比在儿童中更常见。银屑病在地理区域的分布不均；在高收入国家和人口老龄化地区更为常见。提供的估计值可以帮助指导国家和国际社会在制定有关银屑病适当管理的公共卫生决策以及评估其随时间推移的自然史时做出决策。
PROSPERO CRD42019160817。
