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建模影响莫桑比克苏斯登达尼亚疟疾流行的社会人口因素:一项横断面研究。

Modelling sociodemographic factors that affect malaria prevalence in Sussundenga, Mozambique: a cross-sectional study.

机构信息

Engineering & Agriculture, 1Instituto Superior de Ciências e Educação a Distância, Beira, Sofala, Mozambique.

School of Public Health, University of Minnesota, Twin City, Minnesota, USA.

出版信息

F1000Res. 2022 Feb 14;11:185. doi: 10.12688/f1000research.75199.2. eCollection 2022.

Abstract

: Malaria is still one of the leading causes of mortality and morbidity in Mozambique with little progress in malaria control over the past 20 years. Sussundenga is one of most affected areas. Malaria transmission has a strong association with environmental and sociodemographic factors. The knowledge of sociodemographic factors that affects malaria, may be used to improve the strategic planning for its control. Currently such studies have not been performed in Sussundenga. Thus, the objective of this study is to model the relationship between malaria and sociodemographic factors in Sussundenga, Mozambique. Houses in the study area were digitalized and enumerated using Google Earth Pro version 7.3. In this study 100 houses were randomly selected to conduct a community survey of parasite prevalence using rapid diagnostic test (RDT). During the survey, a questionnaire was conducted to assess the sociodemographic factors of the participants. Descriptive statistics were analyzed and backward stepwise logistic regression was performed establishing a relationship between positive cases and the factors. The analysis was carried out using SPSS version 20 package. The overall prevalence was 31.6%. Half of the malaria positive cases occurred in age group 5 to 14 years. Previous malaria treatment, population density and age group were significant predictors for the model. The model explained 13.5% of the variance in malaria positive cases and sensitivity of the final model was 73.3%. In this area the highest burden of infection was among those aged 5-14 years old. Malaria infection was related to sociodemographic factors. Targeting malaria control at community level can combat the disease more effectively than waiting for cases at health centers. These finding can be used to guide more effective interventions in this region.

摘要

疟疾仍然是莫桑比克导致死亡和发病的主要原因之一,在过去 20 年里,疟疾控制几乎没有取得进展。苏斯登达是受影响最严重的地区之一。疟疾传播与环境和社会人口因素密切相关。了解影响疟疾的社会人口因素,可用于改善其控制的战略规划。目前,在苏斯登达尚未开展此类研究。因此,本研究的目的是建立莫桑比克苏斯登达地区疟疾与社会人口因素之间的关系模型。

使用谷歌地球专业版 7.3 对研究区域的房屋进行数字化和编号。在这项研究中,随机选择了 100 户房屋,对寄生虫流行率进行了社区调查,采用快速诊断检测(RDT)。在调查过程中,对参与者的社会人口因素进行了问卷调查。对描述性统计数据进行了分析,并进行了向后逐步逻辑回归分析,建立了阳性病例与因素之间的关系。使用 SPSS 版本 20 包进行了分析。总流行率为 31.6%。一半的疟疾病例发生在 5 至 14 岁年龄组。以前的疟疾治疗、人口密度和年龄组是该模型的显著预测因素。该模型解释了疟疾阳性病例 13.5%的方差,最终模型的灵敏度为 73.3%。在该地区,感染负担最高的是 5-14 岁年龄组。疟疾感染与社会人口因素有关。在社区层面上针对疟疾控制可以比在卫生中心等待病例更有效地对抗该疾病。这些发现可用于指导该地区更有效的干预措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9509/9131466/38b5f5b2e6a0/f1000research-11-133640-g0000.jpg

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