韩国零售生鸡肉分离株中质粒介导喹诺酮耐药性（PMQR）和超广谱β-内酰胺酶（ESBL）基因频繁共存的比率。
The rate of frequent co-existence of plasmid-mediated quinolone resistance (PMQR) and extended-spectrum β-lactamase (ESBL) genes in isolates from retail raw chicken in South Korea.
作者信息
Park Hyeeun, Kim Jinshil, Ryu Sangryeol, Jeon Byeonghwa
机构信息
Department of Food and Animal Biotechnology, Department of Agricultural Biotechnology, Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul, 08826 Republic of Korea.
Center for Food and Bioconvergence, Seoul National University, Seoul, 08826 Republic of Korea.
出版信息
Food Sci Biotechnol. 2022 Apr 2;31(6):739-743. doi: 10.1007/s10068-022-01077-0. eCollection 2022 Jun.
Since plasmid-encoded antibiotic resistance facilitates the emergence of antibiotic-resistant bacteria, the increasing prevalence of harboring plasmid-mediated quinolone resistance (PMQR) and extended-spectrum β-lactamase (ESBL) genes is a public health concern. The objective of this study is to investigate the co-existence of PMQR and ESBL genes in isolates from retail raw chicken in South Korea. Among 67 ESBL-producing isolates from 40 retail raw chicken, more than half of them carried PMQR genes, including , ('), and . The was predominantly (91.4%) detected in isolates carrying both PMQR and ESBL. The (') was detected in seven ESBL-producing strains, and 85.7% of the (')-positive strains also carried . Moreover, the strains co-harboring and (') exhibited increased resistance to ciprofloxacin and kanamycin. These results demonstrate that PMQR genes are frequently detected in ESBL-producing isolates from retail raw chicken in South Korea.
由于质粒编码的抗生素耐药性促进了抗生素耐药菌的出现，携带质粒介导的喹诺酮耐药性（PMQR）和超广谱β-内酰胺酶（ESBL）基因的情况日益普遍，这是一个公共卫生问题。本研究的目的是调查韩国零售生鸡肉分离株中PMQR和ESBL基因的共存情况。在来自40份零售生鸡肉的67株产ESBL分离株中，超过一半携带PMQR基因，包括、（'）和。在同时携带PMQR和ESBL的分离株中，主要（91.4%）检测到。在7株产ESBL菌株中检测到（'），且85.7%的（'）阳性菌株也携带。此外，同时携带和（'）的菌株对环丙沙星和卡那霉素的耐药性增加。这些结果表明，在韩国零售生鸡肉的产ESBL分离株中经常检测到PMQR基因。
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