Prevalence of CTX-M types among ESBL-producing pathogenic isolates from foodborne diarrheal patients in Gyeonggi-do, South Korea.

UNLABELLED

Prevalence and characteristics of extended-spectrum β-lactamase (ESBL)-producing pathogenic from foodborne diarrheal patients were studied. Analysis of 495 isolates revealed that 80 isolates were ESBL-producing pathogenic , and enteroaggregative and enterotoxigenic were two of the most prevalent pathotypes. In silico Clermont phylo-typing of the 80 ESBL-producing showed that phylogroup A (49/80) and D (22/80) were the predominant phylogroups. The average nucleotide identity analysis of ESBL-producing disclosed that they could be grouped into two phylogenetic groups; 25 A and 55 B groups. All strains, except one, harbored the CTX-M gene. All CTX-M-15 type ESBL-producing strains also carried , a plasmid-mediated quinolone resistance gene (PMQR). These results suggest that the diversity of ESBL-producing is high and that co-existence of CTX-M-15 and genes is widespread, highlighting their high risk of antibiotic-resistance spreading in infectious disease outbreaks.

SUPPLEMENTARY INFORMATION

The online version contains supplementary material available at 10.1007/s10068-024-01549-5.