Vehawn Jeffrey, Choudry Mouneeb, Mahlow Jonathon, Agarwal Jayant, Dechet Christopher, Sanchez Alejandro
Division of Urology, Department of Surgery, Huntsman Cancer Institute and University of Utah, Salt Lake City, UT, USA.
Department of Pathology, University of Utah, Salt Lake City, UT, USA.
Urol Case Rep. 2022 May 20;43:102120. doi: 10.1016/j.eucr.2022.102120. eCollection 2022 Jul.
A 29-year-old patient presented to his primary care provider complaining of a painful right inguinal swelling. He was referred for inguinal hernia repair, but during surgery, an enlarged necrotic-appearing testicle was observed and removed. Pathology demonstrated a mixed non-seminomatous germ cell tumor (NSGCT) with evidence of tumor violation. After receiving BEPx3 for elevated post-operative AFP his tumor markers normalized. On surveillance, he was found to have several palpable masses around his inguinal incision. On soft tissue excision he was found to have residual teratoma within his soft tissues. We review the literature on germ cell tumor seeding and atypical recurrences.
一名29岁患者因右侧腹股沟肿胀疼痛就诊于其初级保健医生处。他被转诊进行腹股沟疝修补术，但在手术过程中，发现并切除了一个肿大、外观呈坏死样的睾丸。病理检查显示为混合性非精原细胞瘤性生殖细胞肿瘤（NSGCT），并有肿瘤侵犯的证据。术后甲胎蛋白（AFP）升高，接受BEPx3方案治疗后，他的肿瘤标志物恢复正常。在随访过程中，发现他腹股沟切口周围有几个可触及的肿块。软组织切除术后发现其软组织内有残余畸胎瘤。我们回顾了关于生殖细胞肿瘤种植和非典型复发的文献。
